ADAM7-AS1

Summary

ADAM7-AS1 (ADAM7, ADAMDEC1 and ADAM28 antisense RNA 1, HGNC:56152) is a long non-coding RNA gene on chromosome 8p21.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56152
Approved symbol	ADAM7-AS1
Name	ADAM7, ADAMDEC1 and ADAM28 antisense RNA 1
Location	8p21.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000253535
Ensembl biotype	lncRNA
Entrez	101929294
RNAcentral	URS00007E4832 — lncRNA, 887 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000518988, ENST00000519689, ENST00000521681, ENST00000523578, ENST00000523700, ENST00000773556, ENST00000773557, ENST00000773558

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000518988 — 4 exons

Exon	Start	End
ENSE00002090821	24300885	24300929
ENSE00002095497	24295814	24296057
ENSE00002118442	24296154	24296250
ENSE00002139269	24387161	24387515

Expression profiles

Bgee: expression breadth ubiquitous, 124 present calls, max score 83.93.

Top tissues by expression

124 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.93	silver quality
colonic epithelium	UBERON:0000397	82.67	gold quality
bone marrow cell	CL:0002092	77.01	gold quality
bone marrow	UBERON:0002371	72.49	gold quality
tonsil	UBERON:0002372	71.66	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	71.51	gold quality
corpus callosum	UBERON:0002336	70.48	gold quality
lymph node	UBERON:0000029	68.94	gold quality
cortical plate	UBERON:0005343	65.95	gold quality
primary visual cortex	UBERON:0002436	64.78	gold quality
rectum	UBERON:0001052	64.15	gold quality
prefrontal cortex	UBERON:0000451	63.53	gold quality
vermiform appendix	UBERON:0001154	63.21	gold quality
cerebellar cortex	UBERON:0002129	63.06	gold quality
cerebellar hemisphere	UBERON:0002245	63.06	gold quality
cerebellum	UBERON:0002037	63.04	gold quality
superior frontal gyrus	UBERON:0002661	62.64	gold quality
Brodmann (1909) area 9	UBERON:0013540	62.51	gold quality
right hemisphere of cerebellum	UBERON:0014890	61.94	gold quality
frontal cortex	UBERON:0001870	61.16	gold quality
ganglionic eminence	UBERON:0004023	60.91	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	60.76	gold quality
cerebral cortex	UBERON:0000956	59.47	gold quality
calcaneal tendon	UBERON:0003701	59.16	gold quality
duodenum	UBERON:0002114	58.70	gold quality
small intestine	UBERON:0002108	58.61	gold quality
nucleus accumbens	UBERON:0001882	58.52	gold quality
blood	UBERON:0000178	58.33	gold quality
small intestine Peyer’s patch	UBERON:0003454	58.03	gold quality
monocyte	CL:0000576	57.89	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-HCAD-25	yes	2581.33
E-ANND-3	yes	14.27

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.