ADAMTS3-AS1

Summary

ADAMTS3-AS1 (ADAMTS3 antisense RNA 1, HGNC:40063) is a long non-coding RNA gene on chromosome 4q13.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40063
Approved symbol	ADAMTS3-AS1
Name	ADAMTS3 antisense RNA 1
Location	4q13.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000250877
Ensembl biotype	lncRNA
Entrez	144093400

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000503918

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000503918 — 2 exons

Exon	Start	End
ENSE00002028800	72323028	72323187
ENSE00002029076	72330487	72330751

Expression profiles

Bgee: expression breadth broad, 76 present calls, max score 64.94.

Top tissues by expression

76 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
calcaneal tendon	UBERON:0003701	64.94	gold quality
tonsil	UBERON:0002372	61.29	silver quality
bone marrow	UBERON:0002371	60.68	gold quality
adrenal tissue	UBERON:0018303	58.32	gold quality
blood	UBERON:0000178	57.31	gold quality
monocyte	CL:0000576	55.59	gold quality
prefrontal cortex	UBERON:0000451	55.52	gold quality
kidney	UBERON:0002113	55.44	gold quality
cortex of kidney	UBERON:0001225	54.59	gold quality
corpus callosum	UBERON:0002336	53.95	gold quality
endometrium	UBERON:0001295	53.43	gold quality
gastrocnemius	UBERON:0001388	52.07	gold quality
adrenal gland	UBERON:0002369	50.23	gold quality
smooth muscle tissue	UBERON:0001135	49.72	gold quality
left coronary artery	UBERON:0001626	49.55	gold quality
tibial artery	UBERON:0007610	49.03	gold quality
anterior cingulate cortex	UBERON:0009835	47.98	gold quality
thoracic mammary gland	UBERON:0005200	47.58	gold quality
body of pancreas	UBERON:0001150	47.20	silver quality
lower esophagus muscularis layer	UBERON:0035833	46.79	gold quality
descending thoracic aorta	UBERON:0002345	46.65	gold quality
body of stomach	UBERON:0001161	46.38	gold quality
ovary	UBERON:0000992	46.36	gold quality
esophagus mucosa	UBERON:0002469	46.32	gold quality
heart	UBERON:0000948	46.28	silver quality
left ovary	UBERON:0002119	46.17	gold quality
adenohypophysis	UBERON:0002196	45.24	gold quality
body of uterus	UBERON:0009853	45.12	gold quality
subcutaneous adipose tissue	UBERON:0002190	45.09	gold quality
hypothalamus	UBERON:0001898	45.08	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.48

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.