ADAMTSL4-AS2

Summary

ADAMTSL4-AS2 (ADAMTSL4 antisense RNA 2, HGNC:40895) is a long non-coding RNA gene on chromosome 1q21.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40895
Approved symbol	ADAMTSL4-AS2
Name	ADAMTSL4 antisense RNA 2
Location	1q21.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000237781
Ensembl biotype	lncRNA
Entrez	100289061
RNAcentral	URS00004019BC — lncRNA, 663 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000442435

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000442435 — 6 exons

Exon	Start	End
ENSE00001599721	150556148	150556217
ENSE00001601706	150556608	150556684
ENSE00001690649	150555954	150556052
ENSE00001725056	150554535	150554732
ENSE00001753812	150557693	150557724
ENSE00001801305	150548562	150548750

Expression profiles

Bgee: expression breadth ubiquitous, 157 present calls, max score 85.72.

Top tissues by expression

242 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	85.72	gold quality
mucosa of stomach	UBERON:0001199	83.85	gold quality
left uterine tube	UBERON:0001303	82.82	gold quality
blood	UBERON:0000178	80.46	gold quality
right uterine tube	UBERON:0001302	80.45	gold quality
descending thoracic aorta	UBERON:0002345	78.89	gold quality
spleen	UBERON:0002106	78.81	gold quality
upper lobe of left lung	UBERON:0008952	78.22	gold quality
minor salivary gland	UBERON:0001830	77.50	gold quality
omental fat pad	UBERON:0010414	77.48	gold quality
peritoneum	UBERON:0002358	77.38	gold quality
ascending aorta	UBERON:0001496	77.36	gold quality
thoracic aorta	UBERON:0001515	77.22	gold quality
left coronary artery	UBERON:0001626	76.13	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	76.12	gold quality
right lung	UBERON:0002167	76.11	gold quality
lower esophagus mucosa	UBERON:0035834	76.01	gold quality
tibial nerve	UBERON:0001323	75.86	gold quality
saliva-secreting gland	UBERON:0001044	75.81	gold quality
buccal mucosa cell	CL:0002336	75.78	gold quality
adipose tissue of abdominal region	UBERON:0007808	75.66	gold quality
body of uterus	UBERON:0009853	75.49	gold quality
upper lobe of lung	UBERON:0008948	75.30	gold quality
aorta	UBERON:0000947	75.22	gold quality
lower esophagus muscularis layer	UBERON:0035833	75.17	gold quality
lower esophagus	UBERON:0013473	75.12	gold quality
granulocyte	CL:0000094	74.95	gold quality
ectocervix	UBERON:0012249	74.85	gold quality
right coronary artery	UBERON:0001625	74.75	gold quality
esophagus mucosa	UBERON:0002469	74.60	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.57

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.