ADARB2-AS1

Summary

ADARB2-AS1 (ADARB2 antisense RNA 1, HGNC:23299) is a long non-coding RNA gene on chromosome 10p15.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:23299
Approved symbol	ADARB2-AS1
Name	ADARB2 antisense RNA 1
Location	10p15.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	bA466B20.1
Ensembl gene	ENSG00000205696
Ensembl biotype	lncRNA
Entrez	642394
RNAcentral	URS0000CCE155 — lncRNA, 668 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000381301, ENST00000421697, ENST00000692429, ENST00000754241, ENST00000754242, ENST00000754243, ENST00000754244, ENST00000784177

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000381301 — 3 exons

Exon	Start	End
ENSE00001488102	1535592	1535673
ENSE00001488104	1534590	1534995
ENSE00001562565	1526763	1526899

Expression profiles

Bgee: expression breadth broad, 96 present calls, max score 83.43.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.3314 / max 79.4141, expressed in 68 samples.

FANTOM5 promoters (6 alternative TSS)

Promoter ID	TPM avg	Samples expressed
103446	0.1537	49
103445	0.0534	30
103444	0.0516	25
103443	0.0334	7
103447	0.0199	12
103442	0.0194	7

Top tissues by expression

192 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
C1 segment of cervical spinal cord	UBERON:0006469	83.43	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.72	silver quality
spinal cord	UBERON:0002240	80.35	gold quality
substantia nigra	UBERON:0002038	73.93	gold quality
buccal mucosa cell	CL:0002336	73.17	gold quality
midbrain	UBERON:0001891	70.59	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	68.20	gold quality
putamen	UBERON:0001874	66.68	gold quality
caudate nucleus	UBERON:0001873	63.54	gold quality
upper leg skin	UBERON:0004262	62.91	silver quality
amygdala	UBERON:0001876	62.87	gold quality
hypothalamus	UBERON:0001898	62.77	gold quality
ganglionic eminence	UBERON:0004023	62.77	gold quality
Brodmann (1909) area 9	UBERON:0013540	62.43	gold quality
corpus callosum	UBERON:0002336	60.69	gold quality
Ammon’s horn	UBERON:0001954	59.21	gold quality
oocyte	CL:0000023	59.02	gold quality
superficial temporal artery	UBERON:0001614	58.85	gold quality
sural nerve	UBERON:0015488	58.37	silver quality
prefrontal cortex	UBERON:0000451	57.64	gold quality
nucleus accumbens	UBERON:0001882	57.48	gold quality
anterior cingulate cortex	UBERON:0009835	56.75	gold quality
pons	UBERON:0000988	56.35	gold quality
brain	UBERON:0000955	56.26	gold quality
sperm	CL:0000019	56.07	gold quality
body of tongue	UBERON:0011876	56.00	gold quality
forebrain	UBERON:0001890	55.95	gold quality
nasal cavity mucosa	UBERON:0001826	55.88	silver quality
monocyte	CL:0000576	55.80	gold quality
right frontal lobe	UBERON:0002810	55.49	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.29

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.