ADD2-AS1

Summary

ADD2-AS1 (ADD2 antisense RNA 1, HGNC:40065) is a long non-coding RNA gene on chromosome 2p13.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40065
Approved symbol	ADD2-AS1
Name	ADD2 antisense RNA 1
Location	2p13.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235035
Ensembl biotype	lncRNA
Entrez	141585756

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000457851

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000457851 — 2 exons

Exon	Start	End
ENSE00001662896	70687142	70687358
ENSE00001739731	70691608	70691824

Expression profiles

Bgee: expression breadth broad, 63 present calls, max score 97.91.

Top tissues by expression

63 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	97.91	gold quality
ganglionic eminence	UBERON:0004023	66.48	gold quality
bone marrow cell	CL:0002092	62.65	silver quality
lymph node	UBERON:0000029	61.75	gold quality
monocyte	CL:0000576	59.83	gold quality
bone marrow	UBERON:0002371	58.96	gold quality
placenta	UBERON:0001987	55.33	gold quality
blood	UBERON:0000178	54.51	gold quality
adrenal tissue	UBERON:0018303	52.63	gold quality
corpus callosum	UBERON:0002336	51.53	gold quality
prefrontal cortex	UBERON:0000451	50.35	gold quality
gastrocnemius	UBERON:0001388	50.02	gold quality
cerebellum	UBERON:0002037	49.12	gold quality
cerebellar cortex	UBERON:0002129	49.08	gold quality
cerebellar hemisphere	UBERON:0002245	49.00	gold quality
heart	UBERON:0000948	47.35	silver quality
right hemisphere of cerebellum	UBERON:0014890	46.36	silver quality
body of stomach	UBERON:0001161	45.95	gold quality
myometrium	UBERON:0001296	45.83	silver quality
heart left ventricle	UBERON:0002084	45.52	silver quality
Ammon’s horn	UBERON:0001954	45.42	gold quality
brain	UBERON:0000955	44.86	gold quality
subcutaneous adipose tissue	UBERON:0002190	44.70	silver quality
body of pancreas	UBERON:0001150	44.64	silver quality
putamen	UBERON:0001874	43.77	gold quality
nucleus accumbens	UBERON:0001882	43.21	gold quality
hypothalamus	UBERON:0001898	43.20	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	42.97	silver quality
lower esophagus muscularis layer	UBERON:0035833	42.78	silver quality
minor salivary gland	UBERON:0001830	42.68	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.64

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.