ADGRL1-AS1

Summary

ADGRL1-AS1 (ADGRL1 antisense RNA 1, HGNC:55309) is a long non-coding RNA gene on chromosome 19p13.12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55309
Approved symbol	ADGRL1-AS1
Name	ADGRL1 antisense RNA 1
Location	19p13.12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000267169
Ensembl biotype	lncRNA
Entrez	100507373
RNAcentral	URS000075C058 — lncRNA, 2904 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000588387, ENST00000588658, ENST00000592086

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000588387 — 3 exons

Exon	Start	End
ENSE00002773383	14155152	14155479
ENSE00004124186	14168777	14171264
ENSE00004124189	14137145	14137223

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 83.47.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 7.3331 / max 132.1456, expressed in 1719 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
174222	6.9084	1709
174223	0.4247	196

Top tissues by expression

134 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	83.47	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.18	gold quality
monocyte	CL:0000576	80.54	gold quality
granulocyte	CL:0000094	80.45	gold quality
leukocyte	CL:0000738	80.06	gold quality
blood	UBERON:0000178	79.24	gold quality
right hemisphere of cerebellum	UBERON:0014890	77.21	gold quality
cerebellar hemisphere	UBERON:0002245	76.76	gold quality
cerebellum	UBERON:0002037	76.72	gold quality
cerebellar cortex	UBERON:0002129	76.64	gold quality
stromal cell of endometrium	CL:0002255	76.00	gold quality
bone marrow cell	CL:0002092	74.56	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	74.11	gold quality
bone marrow	UBERON:0002371	73.45	gold quality
spleen	UBERON:0002106	73.28	gold quality
substantia nigra	UBERON:0002038	72.31	gold quality
pituitary gland	UBERON:0000007	71.93	gold quality
tibial nerve	UBERON:0001323	71.92	gold quality
body of uterus	UBERON:0009853	71.85	gold quality
myometrium	UBERON:0001296	71.68	gold quality
muscle layer of sigmoid colon	UBERON:0035805	71.65	gold quality
right ovary	UBERON:0002118	71.63	gold quality
lower esophagus muscularis layer	UBERON:0035833	71.61	gold quality
lower esophagus	UBERON:0013473	71.58	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	71.57	gold quality
amygdala	UBERON:0001876	71.48	gold quality
temporal lobe	UBERON:0001871	71.45	gold quality
descending thoracic aorta	UBERON:0002345	71.44	gold quality
uterine cervix	UBERON:0000002	71.40	gold quality
left ovary	UBERON:0002119	71.39	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.06

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.