ADGRL3-AS1

Summary

ADGRL3-AS1 (ADGRL3 antisense RNA 1, HGNC:50604) is a long non-coding RNA gene on chromosome 4q13.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50604
Approved symbol	ADGRL3-AS1
Name	ADGRL3 antisense RNA 1
Location	4q13.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000248692
Ensembl biotype	lncRNA
Entrez	101927186
RNAcentral	URS000075B27D — lncRNA, 467 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000502339, ENST00000504135, ENST00000506704, ENST00000509461, ENST00000801748

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000502339 — 3 exons

Exon	Start	End
ENSE00002028994	62136666	62136756
ENSE00002058044	62117905	62118102
ENSE00002087997	62120228	62120289

Expression profiles

Bgee: expression breadth broad, 93 present calls, max score 79.34.

Top tissues by expression

93 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.34	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	71.58	gold quality
muscle tissue	UBERON:0002385	68.85	gold quality
left testis	UBERON:0004533	67.95	gold quality
testis	UBERON:0000473	67.47	gold quality
sural nerve	UBERON:0015488	65.57	silver quality
right testis	UBERON:0004534	63.94	gold quality
primary visual cortex	UBERON:0002436	62.54	gold quality
heart left ventricle	UBERON:0002084	62.16	gold quality
prefrontal cortex	UBERON:0000451	61.16	gold quality
heart	UBERON:0000948	61.09	gold quality
stromal cell of endometrium	CL:0002255	59.65	gold quality
right atrium auricular region	UBERON:0006631	58.85	gold quality
apex of heart	UBERON:0002098	55.59	gold quality
superior frontal gyrus	UBERON:0002661	55.58	gold quality
duodenum	UBERON:0002114	54.59	gold quality
Brodmann (1909) area 9	UBERON:0013540	53.64	gold quality
monocyte	CL:0000576	53.24	gold quality
endometrium	UBERON:0001295	53.13	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	52.90	gold quality
putamen	UBERON:0001874	52.88	gold quality
frontal cortex	UBERON:0001870	52.87	gold quality
adrenal tissue	UBERON:0018303	52.77	gold quality
blood	UBERON:0000178	52.53	gold quality
multicellular organism	UBERON:0000468	52.47	gold quality
tibial artery	UBERON:0007610	52.39	gold quality
popliteal artery	UBERON:0002250	52.32	gold quality
cerebral cortex	UBERON:0000956	52.13	gold quality
caudate nucleus	UBERON:0001873	51.68	gold quality
nucleus accumbens	UBERON:0001882	51.52	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.26

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.