ADNP-AS1

Summary

ADNP-AS1 (ADNP antisense RNA 1, HGNC:51227) is a long non-coding RNA gene on chromosome 20q13.13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51227
Approved symbol	ADNP-AS1
Name	ADNP antisense RNA 1
Location	20q13.13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259456
Ensembl biotype	lncRNA
Entrez	101927631
RNAcentral	URS000075E7BC — lncRNA, 939 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 29 — 29 lncRNA

ENST00000558899, ENST00000614698, ENST00000655542, ENST00000664246, ENST00000747459, ENST00000747460, ENST00000747461, ENST00000747462, ENST00000747463, ENST00000747464, ENST00000747465, ENST00000747466, ENST00000747467, ENST00000747468, ENST00000747469, ENST00000747470, ENST00000747471, ENST00000747472, ENST00000747473, ENST00000747474, ENST00000747475, ENST00000747476, ENST00000747477, ENST00000747478, ENST00000747479, ENST00000747480, ENST00000747481, ENST00000747482, ENST00000747483

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000558899 — 3 exons

Exon	Start	End
ENSE00002541073	50931372	50931449
ENSE00002555858	50944357	50945134
ENSE00002561467	50930984	50931054

Expression profiles

Bgee: expression breadth ubiquitous, 136 present calls, max score 87.42.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2639 / max 22.1598, expressed in 73 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
185294	0.2639	73

Top tissues by expression

138 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left testis	UBERON:0004533	87.42	gold quality
right testis	UBERON:0004534	87.01	gold quality
testis	UBERON:0000473	86.91	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.76	gold quality
cerebellar hemisphere	UBERON:0002245	78.09	gold quality
cerebellar cortex	UBERON:0002129	78.06	gold quality
cerebellum	UBERON:0002037	77.97	gold quality
right hemisphere of cerebellum	UBERON:0014890	77.88	gold quality
colonic epithelium	UBERON:0000397	75.84	gold quality
bone marrow	UBERON:0002371	75.76	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	73.66	gold quality
spinal cord	UBERON:0002240	73.59	gold quality
monocyte	CL:0000576	73.50	gold quality
nucleus accumbens	UBERON:0001882	73.41	gold quality
bone marrow cell	CL:0002092	73.26	gold quality
leukocyte	CL:0000738	73.24	gold quality
gastrocnemius	UBERON:0001388	73.02	gold quality
cortical plate	UBERON:0005343	72.94	gold quality
endometrium	UBERON:0001295	72.82	gold quality
muscle of leg	UBERON:0001383	72.43	gold quality
skeletal muscle tissue	UBERON:0001134	72.26	gold quality
left lobe of thyroid gland	UBERON:0001120	72.20	gold quality
thyroid gland	UBERON:0002046	72.19	gold quality
body of pancreas	UBERON:0001150	72.14	gold quality
hindlimb stylopod muscle	UBERON:0004252	72.08	gold quality
amygdala	UBERON:0001876	71.83	gold quality
left ovary	UBERON:0002119	71.80	gold quality
lower esophagus mucosa	UBERON:0035834	71.73	gold quality
putamen	UBERON:0001874	71.70	gold quality
right ovary	UBERON:0002118	71.70	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.97

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.