AFAP1-AS2

Summary

AFAP1-AS2 (AFAP1 antisense RNA 2, HGNC:58726) is a long non-coding RNA gene on chromosome 4p16.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58726
Approved symbol	AFAP1-AS2
Name	AFAP1 antisense RNA 2
Location	4p16.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000287164
Ensembl biotype	lncRNA
Entrez	124900656

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000669561, ENST00000749287, ENST00000749288, ENST00000749289

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000669561 — 2 exons

Exon	Start	End
ENSE00004092841	7798521	7798718
ENSE00004092843	7807647	7808053

Expression profiles

Bgee: expression breadth ubiquitous, 101 present calls, max score 87.14.

Top tissues by expression

101 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.14	gold quality
colonic epithelium	UBERON:0000397	70.99	silver quality
skeletal muscle tissue	UBERON:0001134	70.03	gold quality
sural nerve	UBERON:0015488	69.79	gold quality
bone marrow cell	CL:0002092	66.79	silver quality
monocyte	CL:0000576	64.47	gold quality
leukocyte	CL:0000738	64.21	gold quality
bone marrow	UBERON:0002371	60.40	silver quality
urinary bladder	UBERON:0001255	57.82	silver quality
islet of Langerhans	UBERON:0000006	55.84	gold quality
testis	UBERON:0000473	55.70	gold quality
right testis	UBERON:0004534	55.70	gold quality
liver	UBERON:0002107	55.67	silver quality
left testis	UBERON:0004533	55.64	gold quality
blood	UBERON:0000178	54.19	gold quality
calcaneal tendon	UBERON:0003701	53.05	silver quality
adenohypophysis	UBERON:0002196	52.62	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.62	gold quality
primary visual cortex	UBERON:0002436	50.64	gold quality
adrenal tissue	UBERON:0018303	50.53	silver quality
superior frontal gyrus	UBERON:0002661	50.39	gold quality
placenta	UBERON:0001987	50.07	gold quality
prefrontal cortex	UBERON:0000451	49.97	gold quality
ectocervix	UBERON:0012249	49.95	gold quality
muscle of leg	UBERON:0001383	48.45	gold quality
corpus callosum	UBERON:0002336	48.33	silver quality
granulocyte	CL:0000094	48.27	silver quality
gastrocnemius	UBERON:0001388	47.90	gold quality
multicellular organism	UBERON:0000468	47.46	gold quality
lung	UBERON:0002048	46.97	gold quality

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.