AFF4-DT

Summary

AFF4-DT (AFF4 divergent transcript, HGNC:55235) is a long non-coding RNA gene on chromosome 5q31.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55235
Approved symbol	AFF4-DT
Name	AFF4 divergent transcript
Location	5q31.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000272023
Ensembl biotype	lncRNA
Entrez	124901065
RNAcentral	URS00026A24E9 — lncRNA, 773 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000607688, ENST00000810652, ENST00000810653, ENST00000810654

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000607688 — 1 exons

Exon	Start	End
ENSE00003699435	132963770	132964164

Expression profiles

Bgee: expression breadth ubiquitous, 108 present calls, max score 85.17.

Top tissues by expression

108 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.17	gold quality
cortical plate	UBERON:0005343	70.12	gold quality
bone marrow cell	CL:0002092	68.06	silver quality
bone marrow	UBERON:0002371	64.51	gold quality
stromal cell of endometrium	CL:0002255	62.66	gold quality
granulocyte	CL:0000094	60.34	gold quality
monocyte	CL:0000576	57.57	gold quality
prefrontal cortex	UBERON:0000451	56.61	gold quality
islet of Langerhans	UBERON:0000006	55.60	gold quality
vermiform appendix	UBERON:0001154	55.20	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	54.77	gold quality
mucosa of transverse colon	UBERON:0004991	53.93	gold quality
sural nerve	UBERON:0015488	53.93	silver quality
lymph node	UBERON:0000029	53.26	gold quality
tonsil	UBERON:0002372	53.10	gold quality
blood	UBERON:0000178	52.98	gold quality
primary visual cortex	UBERON:0002436	51.47	gold quality
kidney	UBERON:0002113	51.10	gold quality
adult mammalian kidney	UBERON:0000082	50.87	gold quality
liver	UBERON:0002107	50.81	gold quality
right lung	UBERON:0002167	50.69	gold quality
left adrenal gland cortex	UBERON:0035825	49.67	gold quality
muscle of leg	UBERON:0001383	49.64	gold quality
gastrocnemius	UBERON:0001388	49.32	gold quality
right adrenal gland	UBERON:0001233	49.12	gold quality
adrenal gland	UBERON:0002369	48.87	gold quality
left adrenal gland	UBERON:0001234	48.52	gold quality
tibial artery	UBERON:0007610	48.06	gold quality
popliteal artery	UBERON:0002250	48.02	gold quality
left coronary artery	UBERON:0001626	47.90	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.76

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.