AFTPH-DT

Summary

AFTPH-DT (AFTPH divergent transcript, HGNC:52788) is a long non-coding RNA gene on chromosome 2p14.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52788
Approved symbol	AFTPH-DT
Name	AFTPH divergent transcript
Location	2p14
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000260101
Ensembl biotype	lncRNA
Entrez	101927402
RNAcentral	URS0000A76F9F — lncRNA, 1981 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000561559, ENST00000789328, ENST00000789329, ENST00000789330, ENST00000789331

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000561559 — 1 exons

Exon	Start	End
ENSE00004168550	64522187	64524785

Expression profiles

Bgee: expression breadth ubiquitous, 167 present calls, max score 88.64.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.3381 / max 19.3967, expressed in 159 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
28759	0.3197	148
28760	0.0183	5

Top tissues by expression

242 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	88.64	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	82.10	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.78	gold quality
pancreatic ductal cell	CL:0002079	75.25	silver quality
monocyte	CL:0000576	73.15	gold quality
leukocyte	CL:0000738	73.06	gold quality
left testis	UBERON:0004533	71.89	gold quality
right testis	UBERON:0004534	70.83	gold quality
testis	UBERON:0000473	70.36	gold quality
bone marrow cell	CL:0002092	70.31	gold quality
lymph node	UBERON:0000029	68.74	gold quality
granulocyte	CL:0000094	66.95	gold quality
vermiform appendix	UBERON:0001154	66.70	gold quality
tonsil	UBERON:0002372	65.36	gold quality
colonic epithelium	UBERON:0000397	63.79	silver quality
buccal mucosa cell	CL:0002336	63.29	silver quality
epithelial cell of pancreas	CL:0000083	63.20	silver quality
caecum	UBERON:0001153	62.21	gold quality
amniotic fluid	UBERON:0000173	62.04	gold quality
cortical plate	UBERON:0005343	61.83	gold quality
upper arm skin	UBERON:0004263	61.71	gold quality
esophagus squamous epithelium	UBERON:0006920	61.71	silver quality
prefrontal cortex	UBERON:0000451	61.64	gold quality
rectum	UBERON:0001052	61.48	gold quality
gall bladder	UBERON:0002110	61.12	gold quality
gingival epithelium	UBERON:0001949	61.02	gold quality
gingiva	UBERON:0001828	60.78	silver quality
epithelium of nasopharynx	UBERON:0001951	60.51	silver quality
tibialis anterior	UBERON:0001385	59.89	silver quality
skin of hip	UBERON:0001554	59.15	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.74

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.