AGA-DT

Summary

AGA-DT (AGA divergent transcript, HGNC:27730) is a long non-coding RNA gene on chromosome 4q34.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27730
Approved symbol	AGA-DT
Name	AGA divergent transcript
Location	4q34.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000250131
Ensembl biotype	lncRNA
Entrez	285500
RNAcentral	URS00026A235F — lncRNA, 2136 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 10 lncRNA

ENST00000507023, ENST00000654463, ENST00000668108, ENST00000671080, ENST00000829578, ENST00000829579, ENST00000829580, ENST00000829581, ENST00000829582, ENST00000829583

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000507023 — 6 exons

Exon	Start	End
ENSE00002021952	177444979	177445443
ENSE00002024657	177596461	177596531
ENSE00002039218	177593472	177593546
ENSE00002071989	177623659	177623802
ENSE00002078888	177675837	177677126
ENSE00002087787	177451475	177451590

Expression profiles

Bgee: expression breadth ubiquitous, 159 present calls, max score 79.34.

Top tissues by expression

245 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.34	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	78.97	gold quality
sural nerve	UBERON:0015488	65.54	silver quality
colonic epithelium	UBERON:0000397	64.47	silver quality
ventricular zone	UBERON:0003053	64.32	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	63.72	gold quality
bone marrow cell	CL:0002092	63.41	silver quality
cortical plate	UBERON:0005343	63.01	gold quality
monocyte	CL:0000576	62.25	gold quality
ganglionic eminence	UBERON:0004023	62.23	gold quality
leukocyte	CL:0000738	61.96	gold quality
islet of Langerhans	UBERON:0000006	61.91	gold quality
spinal cord	UBERON:0002240	61.58	gold quality
stromal cell of endometrium	CL:0002255	58.80	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	58.79	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.39	gold quality
prefrontal cortex	UBERON:0000451	58.02	gold quality
granulocyte	CL:0000094	57.82	gold quality
amygdala	UBERON:0001876	57.24	gold quality
skin of abdomen	UBERON:0001416	56.34	gold quality
putamen	UBERON:0001874	56.29	gold quality
skin of leg	UBERON:0001511	56.20	gold quality
rectum	UBERON:0001052	56.13	gold quality
left adrenal gland cortex	UBERON:0035825	55.92	gold quality
right adrenal gland cortex	UBERON:0035827	55.88	gold quality
tibial nerve	UBERON:0001323	55.66	gold quality
nucleus accumbens	UBERON:0001882	55.56	gold quality
substantia nigra	UBERON:0002038	55.50	gold quality
esophagus mucosa	UBERON:0002469	55.46	gold quality
hypothalamus	UBERON:0001898	55.26	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.71

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.