AGAP1-IT1

Summary

AGAP1-IT1 (AGAP1 intronic transcript 1, HGNC:41427) is a long non-coding RNA gene on chromosome 2q37.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41427
Approved symbol	AGAP1-IT1
Name	AGAP1 intronic transcript 1
Location	2q37.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235529
Ensembl biotype	lncRNA
Entrez	100506749
RNAcentral	URS00008E3A47 — lncRNA, 683 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000440498, ENST00000690935

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000440498 — 2 exons

Exon	Start	End
ENSE00001663949	235506953	235507566
ENSE00001738970	235505751	235505800

Expression profiles

Bgee: expression breadth ubiquitous, 125 present calls, max score 79.52.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0121 / max 12.8225, expressed in 1 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
26191	0.0121	1

Top tissues by expression

125 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	79.52	gold quality
colonic epithelium	UBERON:0000397	74.52	gold quality
bone marrow cell	CL:0002092	72.36	silver quality
mucosa of transverse colon	UBERON:0004991	69.72	gold quality
skeletal muscle tissue	UBERON:0001134	66.28	silver quality
liver	UBERON:0002107	65.61	gold quality
muscle tissue	UBERON:0002385	64.73	gold quality
rectum	UBERON:0001052	64.38	gold quality
ventricular zone	UBERON:0003053	63.50	gold quality
right lobe of liver	UBERON:0001114	62.78	gold quality
kidney	UBERON:0002113	61.17	gold quality
stromal cell of endometrium	CL:0002255	60.97	gold quality
adult mammalian kidney	UBERON:0000082	60.44	gold quality
hindlimb stylopod muscle	UBERON:0004252	60.43	gold quality
bone marrow	UBERON:0002371	59.27	silver quality
transverse colon	UBERON:0001157	58.22	gold quality
tonsil	UBERON:0002372	57.80	gold quality
cortex of kidney	UBERON:0001225	57.38	gold quality
lung	UBERON:0002048	57.15	gold quality
islet of Langerhans	UBERON:0000006	56.99	gold quality
vermiform appendix	UBERON:0001154	56.76	gold quality
stomach	UBERON:0000945	56.58	gold quality
colon	UBERON:0001155	56.15	gold quality
gall bladder	UBERON:0002110	56.09	gold quality
intestine	UBERON:0000160	55.97	gold quality
placenta	UBERON:0001987	55.60	gold quality
body of stomach	UBERON:0001161	55.49	gold quality
adrenal tissue	UBERON:0018303	55.27	gold quality
upper lobe of left lung	UBERON:0008952	55.22	gold quality
small intestine	UBERON:0002108	55.07	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.06

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.