AGBL1-AS1

Summary

AGBL1-AS1 (AGBL1 antisense RNA 1, HGNC:48617) is a long non-coding RNA gene on chromosome 15q25.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48617
Approved symbol	AGBL1-AS1
Name	AGBL1 antisense RNA 1
Location	15q25.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000260125
Ensembl biotype	lncRNA
Entrez	727915
RNAcentral	URS000075E9BB — lncRNA, 905 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000563472, ENST00000564487, ENST00000566878

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000563472 — 3 exons

Exon	Start	End
ENSE00002622648	86304912	86305084
ENSE00004038214	86316730	86317173
ENSE00004038215	86296829	86297074

Expression profiles

Bgee: expression breadth broad, 94 present calls, max score 83.67.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0159 / max 13.5325, expressed in 4 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
151366	0.0159	4

Top tissues by expression

94 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.67	gold quality
left testis	UBERON:0004533	77.50	gold quality
testis	UBERON:0000473	77.19	gold quality
right testis	UBERON:0004534	76.44	gold quality
skeletal muscle tissue	UBERON:0001134	73.61	gold quality
hindlimb stylopod muscle	UBERON:0004252	67.23	gold quality
adrenal tissue	UBERON:0018303	66.24	gold quality
sural nerve	UBERON:0015488	66.19	silver quality
colonic epithelium	UBERON:0000397	60.83	silver quality
muscle of leg	UBERON:0001383	59.32	gold quality
cortical plate	UBERON:0005343	59.09	silver quality
left ovary	UBERON:0002119	58.99	gold quality
corpus callosum	UBERON:0002336	58.88	gold quality
ganglionic eminence	UBERON:0004023	58.87	silver quality
gastrocnemius	UBERON:0001388	58.78	gold quality
monocyte	CL:0000576	56.58	gold quality
endometrium	UBERON:0001295	54.83	silver quality
multicellular organism	UBERON:0000468	54.35	gold quality
liver	UBERON:0002107	53.31	silver quality
prefrontal cortex	UBERON:0000451	52.68	gold quality
urinary bladder	UBERON:0001255	51.69	silver quality
adult mammalian kidney	UBERON:0000082	51.49	gold quality
adrenal gland	UBERON:0002369	51.49	gold quality
left coronary artery	UBERON:0001626	51.11	gold quality
ectocervix	UBERON:0012249	50.92	gold quality
islet of Langerhans	UBERON:0000006	50.29	gold quality
right lobe of liver	UBERON:0001114	50.24	gold quality
pancreas	UBERON:0001264	50.20	gold quality
blood	UBERON:0000178	49.59	silver quality
prostate gland	UBERON:0002367	49.28	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.94

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.