AGBL4-IT1

Summary

AGBL4-IT1 (AGBL4 intronic transcript 1, HGNC:41482) is a long non-coding RNA gene on chromosome 1p33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41482
Approved symbol	AGBL4-IT1
Name	AGBL4 intronic transcript 1
Location	1p33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000225623
Ensembl biotype	lncRNA
Entrez	100874313
RNAcentral	URS00001BDE86 — lncRNA, 514 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000457061

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000457061 — 4 exons

Exon	Start	End
ENSE00001632958	49423063	49423134
ENSE00001656009	49374201	49374344
ENSE00001774050	49469799	49470006
ENSE00001798923	49471996	49472085

Expression profiles

Bgee: expression breadth broad, 76 present calls, max score 82.51.

Top tissues by expression

76 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.51	gold quality
corpus callosum	UBERON:0002336	60.86	gold quality
superior frontal gyrus	UBERON:0002661	60.76	gold quality
calcaneal tendon	UBERON:0003701	57.24	gold quality
primary visual cortex	UBERON:0002436	55.44	gold quality
adrenal tissue	UBERON:0018303	54.39	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	53.69	gold quality
monocyte	CL:0000576	51.80	gold quality
islet of Langerhans	UBERON:0000006	51.74	gold quality
blood	UBERON:0000178	50.79	silver quality
endometrium	UBERON:0001295	50.55	silver quality
cortex of kidney	UBERON:0001225	50.27	silver quality
adrenal gland	UBERON:0002369	49.86	gold quality
prefrontal cortex	UBERON:0000451	49.82	gold quality
kidney	UBERON:0002113	49.09	silver quality
lower esophagus muscularis layer	UBERON:0035833	47.49	gold quality
heart left ventricle	UBERON:0002084	46.61	gold quality
left ovary	UBERON:0002119	46.38	gold quality
adult mammalian kidney	UBERON:0000082	45.83	gold quality
lung	UBERON:0002048	45.83	gold quality
Brodmann (1909) area 9	UBERON:0013540	45.66	gold quality
stomach	UBERON:0000945	45.12	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	44.96	gold quality
ovary	UBERON:0000992	44.76	silver quality
substantia nigra	UBERON:0002038	44.67	gold quality
heart	UBERON:0000948	44.10	silver quality
frontal cortex	UBERON:0001870	43.99	gold quality
intestine	UBERON:0000160	43.78	silver quality
brain	UBERON:0000955	43.78	gold quality
left adrenal gland	UBERON:0001234	43.63	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.77

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.