AK2-AS1

Summary

AK2-AS1 (AK2 antisense RNA 1, HGNC:58388) is a long non-coding RNA gene on chromosome 1p35.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58388
Approved symbol	AK2-AS1
Name	AK2 antisense RNA 1
Location	1p35.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000236065
Ensembl biotype	lncRNA
Entrez	141585755

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 10 lncRNA

ENST00000427524, ENST00000773302, ENST00000773303, ENST00000773304, ENST00000773305, ENST00000773306, ENST00000773307, ENST00000773308, ENST00000773309, ENST00000773310

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000427524 — 2 exons

Exon	Start	End
ENSE00001657220	32987075	32987319
ENSE00001719815	33031035	33032469

Expression profiles

Bgee: expression breadth broad, 91 present calls, max score 67.67.

Top tissues by expression

189 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	67.67	silver quality
colonic epithelium	UBERON:0000397	62.43	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	61.24	silver quality
hindlimb stylopod muscle	UBERON:0004252	59.36	gold quality
cortical plate	UBERON:0005343	59.31	gold quality
sperm	CL:0000019	56.17	silver quality
cerebellar cortex	UBERON:0002129	55.65	gold quality
cerebellar hemisphere	UBERON:0002245	55.57	gold quality
right hemisphere of cerebellum	UBERON:0014890	55.25	gold quality
cerebellum	UBERON:0002037	54.50	gold quality
adrenal tissue	UBERON:0018303	53.93	gold quality
uterine cervix	UBERON:0000002	52.44	silver quality
lower lobe of lung	UBERON:0008949	52.35	silver quality
stromal cell of endometrium	CL:0002255	52.34	silver quality
tonsil	UBERON:0002372	51.61	silver quality
monocyte	CL:0000576	50.11	silver quality
calcaneal tendon	UBERON:0003701	49.57	silver quality
smooth muscle tissue	UBERON:0001135	49.37	gold quality
left testis	UBERON:0004533	48.98	gold quality
right testis	UBERON:0004534	48.70	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	48.39	gold quality
buccal mucosa cell	CL:0002336	48.25	gold quality
prefrontal cortex	UBERON:0000451	48.04	gold quality
testis	UBERON:0000473	47.81	gold quality
islet of Langerhans	UBERON:0000006	47.38	gold quality
blood	UBERON:0000178	47.24	silver quality
muscle of leg	UBERON:0001383	46.97	gold quality
tendon	UBERON:0000043	46.33	silver quality
right lobe of liver	UBERON:0001114	46.08	silver quality
skeletal muscle tissue	UBERON:0001134	45.66	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.93

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.