AK5-AS1

Summary

AK5-AS1 (AK5 antisense RNA 1, HGNC:40069) is a long non-coding RNA gene on chromosome 1p31.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40069
Approved symbol	AK5-AS1
Name	AK5 antisense RNA 1
Location	1p31.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233099
Ensembl biotype	lncRNA
Entrez	139355236
RNAcentral	URS0002A6F0CA — lncRNA, 650 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000436206, ENST00000810735, ENST00000810736

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000436206 — 2 exons

Exon	Start	End
ENSE00001608137	77346046	77346266
ENSE00001678565	77349430	77349585

Expression profiles

Bgee: expression breadth broad, 74 present calls, max score 91.89.

Top tissues by expression

74 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	91.89	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	89.69	gold quality
corpus callosum	UBERON:0002336	83.07	gold quality
monocyte	CL:0000576	66.54	gold quality
primary visual cortex	UBERON:0002436	65.53	gold quality
bone marrow	UBERON:0002371	62.80	gold quality
prefrontal cortex	UBERON:0000451	61.49	gold quality
right lobe of liver	UBERON:0001114	59.80	gold quality
stromal cell of endometrium	CL:0002255	59.46	gold quality
endometrium	UBERON:0001295	58.23	gold quality
superior frontal gyrus	UBERON:0002661	57.44	gold quality
blood	UBERON:0000178	55.95	gold quality
lower esophagus mucosa	UBERON:0035834	54.64	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	54.02	gold quality
substantia nigra	UBERON:0002038	53.90	gold quality
pancreas	UBERON:0001264	52.83	gold quality
muscle of leg	UBERON:0001383	52.65	gold quality
islet of Langerhans	UBERON:0000006	51.87	gold quality
frontal cortex	UBERON:0001870	51.80	gold quality
gastrocnemius	UBERON:0001388	51.67	gold quality
esophagus mucosa	UBERON:0002469	51.50	gold quality
kidney	UBERON:0002113	51.05	gold quality
thoracic mammary gland	UBERON:0005200	50.30	silver quality
tibial artery	UBERON:0007610	50.30	gold quality
testis	UBERON:0000473	49.80	gold quality
heart left ventricle	UBERON:0002084	49.62	gold quality
liver	UBERON:0002107	49.51	gold quality
multicellular organism	UBERON:0000468	49.26	gold quality
cerebral cortex	UBERON:0000956	48.90	gold quality
putamen	UBERON:0001874	48.79	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.47

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.