AKT3-IT1

Summary

AKT3-IT1 (AKT3 intronic transcript 1, HGNC:41304) is a long non-coding RNA gene on chromosome 1q44.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41304
Approved symbol	AKT3-IT1
Name	AKT3 intronic transcript 1
Location	1q44
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228939
Ensembl biotype	lncRNA
Entrez	100874263
RNAcentral	URS00002C213E — lncRNA, 517 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000417120

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000417120 — 2 exons

Exon	Start	End
ENSE00001647068	243793205	243793580
ENSE00001798322	243794260	243794400

Expression profiles

Bgee: expression breadth ubiquitous, 121 present calls, max score 84.56.

Top tissues by expression

121 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.56	gold quality
colonic epithelium	UBERON:0000397	79.49	gold quality
skeletal muscle tissue	UBERON:0001134	71.68	gold quality
sural nerve	UBERON:0015488	69.64	gold quality
bone marrow cell	CL:0002092	69.34	silver quality
cortical plate	UBERON:0005343	69.05	gold quality
calcaneal tendon	UBERON:0003701	68.29	gold quality
ventricular zone	UBERON:0003053	66.71	gold quality
ganglionic eminence	UBERON:0004023	66.69	gold quality
corpus callosum	UBERON:0002336	66.06	gold quality
bone marrow	UBERON:0002371	64.61	gold quality
tonsil	UBERON:0002372	64.36	gold quality
liver	UBERON:0002107	64.24	gold quality
urinary bladder	UBERON:0001255	63.91	gold quality
islet of Langerhans	UBERON:0000006	60.40	gold quality
granulocyte	CL:0000094	60.30	gold quality
monocyte	CL:0000576	58.69	gold quality
blood	UBERON:0000178	57.16	gold quality
lymph node	UBERON:0000029	56.21	gold quality
stromal cell of endometrium	CL:0002255	55.54	gold quality
kidney	UBERON:0002113	55.08	gold quality
prefrontal cortex	UBERON:0000451	54.99	gold quality
muscle of leg	UBERON:0001383	54.86	gold quality
superior frontal gyrus	UBERON:0002661	54.68	gold quality
adrenal tissue	UBERON:0018303	54.13	gold quality
pancreas	UBERON:0001264	53.24	gold quality
hindlimb stylopod muscle	UBERON:0004252	53.18	gold quality
uterine cervix	UBERON:0000002	52.45	gold quality
cerebellum	UBERON:0002037	51.94	gold quality
cerebellar cortex	UBERON:0002129	51.93	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.22

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.