ALDH1L1-AS2

Summary

ALDH1L1-AS2 (ALDH1L1 antisense RNA 2, HGNC:42446) is a long non-coding RNA gene on chromosome 3q21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42446
Approved symbol	ALDH1L1-AS2
Name	ALDH1L1 antisense RNA 2
Location	3q21.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000246022
Ensembl biotype	lncRNA
Entrez	100862662
RNAcentral	URS000075DB32 — lncRNA, 2325 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000500232, ENST00000500525, ENST00000502278, ENST00000654154, ENST00000725972, ENST00000725973, ENST00000725974, ENST00000725975, ENST00000725976

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000500232 — 2 exons

Exon	Start	End
ENSE00001972121	126180064	126180544
ENSE00002080709	126208326	126210169

Expression profiles

Bgee: expression breadth ubiquitous, 139 present calls, max score 75.00.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.4059 / max 20.9240, expressed in 164 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
38343	0.4059	164

Top tissues by expression

228 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
hindlimb stylopod muscle	UBERON:0004252	75.00	gold quality
heart left ventricle	UBERON:0002084	74.91	gold quality
cardiac ventricle	UBERON:0002082	74.26	gold quality
apex of heart	UBERON:0002098	73.14	gold quality
muscle of leg	UBERON:0001383	71.36	gold quality
gastrocnemius	UBERON:0001388	70.86	gold quality
colonic epithelium	UBERON:0000397	70.82	silver quality
caudate nucleus	UBERON:0001873	68.94	gold quality
putamen	UBERON:0001874	68.78	gold quality
nucleus accumbens	UBERON:0001882	68.72	gold quality
amygdala	UBERON:0001876	68.33	gold quality
heart	UBERON:0000948	68.15	gold quality
right hemisphere of cerebellum	UBERON:0014890	68.13	gold quality
cerebellar hemisphere	UBERON:0002245	67.75	gold quality
cerebellar cortex	UBERON:0002129	67.64	gold quality
descending thoracic aorta	UBERON:0002345	67.60	gold quality
left ovary	UBERON:0002119	67.28	gold quality
ventricular zone	UBERON:0003053	66.80	gold quality
mucosa of stomach	UBERON:0001199	66.71	gold quality
thoracic aorta	UBERON:0001515	66.71	gold quality
anterior cingulate cortex	UBERON:0009835	66.71	gold quality
right ovary	UBERON:0002118	66.68	gold quality
cerebellum	UBERON:0002037	66.65	gold quality
ascending aorta	UBERON:0001496	66.30	gold quality
hypothalamus	UBERON:0001898	66.24	gold quality
substantia nigra	UBERON:0002038	65.90	gold quality
right frontal lobe	UBERON:0002810	65.48	gold quality
omental fat pad	UBERON:0010414	65.32	gold quality
peritoneum	UBERON:0002358	65.25	gold quality
adipose tissue of abdominal region	UBERON:0007808	64.33	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.43

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.