AMANZI

Summary

AMANZI (a master non-coding RNA antagonizing inflammation, HGNC:55634) is a long non-coding RNA gene on chromosome 2q14.1.

At a glance

• Gene type: non-coding (TEC) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55634
Approved symbol	AMANZI
Name	a master non-coding RNA antagonizing inflammation
Location	2q14.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000280228
Ensembl biotype	TEC
Entrez	133395149
RNAcentral	URS0002A147DA — lncRNA, 4412 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 TEC

ENST00000623243

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000623243 — 1 exons

Exon	Start	End
ENSE00003755849	112840328	112844195

Expression profiles

Bgee: expression breadth broad, 41 present calls, max score 72.18.

Top tissues by expression

41 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	72.18	silver quality
bone marrow cell	CL:0002092	70.47	gold quality
granulocyte	CL:0000094	62.81	gold quality
bone marrow	UBERON:0002371	60.42	gold quality
body of stomach	UBERON:0001161	58.10	gold quality
stomach	UBERON:0000945	57.78	gold quality
hindlimb stylopod muscle	UBERON:0004252	55.92	silver quality
monocyte	CL:0000576	54.60	gold quality
stromal cell of endometrium	CL:0002255	52.64	silver quality
muscle layer of sigmoid colon	UBERON:0035805	52.57	gold quality
muscle tissue	UBERON:0002385	50.82	silver quality
blood	UBERON:0000178	49.53	silver quality
fundus of stomach	UBERON:0001160	49.49	gold quality
thyroid gland	UBERON:0002046	48.56	silver quality
lymph node	UBERON:0000029	47.89	silver quality
duodenum	UBERON:0002114	47.69	silver quality
ovary	UBERON:0000992	47.39	silver quality
skin of leg	UBERON:0001511	47.33	gold quality
colon	UBERON:0001155	47.29	gold quality
transverse colon	UBERON:0001157	46.46	gold quality
placenta	UBERON:0001987	45.83	silver quality
vermiform appendix	UBERON:0001154	45.75	silver quality
small intestine Peyer’s patch	UBERON:0003454	45.67	gold quality
urinary bladder	UBERON:0001255	45.09	silver quality
mucosa of stomach	UBERON:0001199	44.08	gold quality
smooth muscle tissue	UBERON:0001135	43.11	gold quality
rectum	UBERON:0001052	41.93	silver quality
gall bladder	UBERON:0002110	41.81	silver quality
skin of abdomen	UBERON:0001416	41.43	silver quality
body of pancreas	UBERON:0001150	41.40	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.57

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.