ANK2-AS1

Summary

ANK2-AS1 (ANK2 antisense RNA 1, HGNC:40076) is a long non-coding RNA gene on chromosome 4q25.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40076
Approved symbol	ANK2-AS1
Name	ANK2 antisense RNA 1
Location	4q25
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000248152
Ensembl biotype	lncRNA
Entrez	105377373
RNAcentral	URS0000EF5569 — lncRNA, 1718 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000508959, ENST00000661685, ENST00000668381

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000508959 — 3 exons

Exon	Start	End
ENSE00002073808	113034683	113034794
ENSE00002079504	112979590	112980528
ENSE00002084859	113071838	113071962

Expression profiles

Bgee: expression breadth ubiquitous, 115 present calls, max score 86.86.

Top tissues by expression

115 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
corpus callosum	UBERON:0002336	86.86	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.37	gold quality
bone marrow cell	CL:0002092	79.72	gold quality
colonic epithelium	UBERON:0000397	77.32	gold quality
sural nerve	UBERON:0015488	73.36	gold quality
calcaneal tendon	UBERON:0003701	67.28	gold quality
skeletal muscle tissue	UBERON:0001134	66.94	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	65.74	gold quality
testis	UBERON:0000473	65.03	gold quality
right testis	UBERON:0004534	65.02	gold quality
left testis	UBERON:0004533	64.91	gold quality
tonsil	UBERON:0002372	63.40	silver quality
bone marrow	UBERON:0002371	62.69	gold quality
adrenal tissue	UBERON:0018303	61.09	gold quality
urinary bladder	UBERON:0001255	60.55	silver quality
primary visual cortex	UBERON:0002436	60.26	gold quality
cortical plate	UBERON:0005343	58.57	silver quality
hindlimb stylopod muscle	UBERON:0004252	57.33	gold quality
superior frontal gyrus	UBERON:0002661	54.86	gold quality
blood	UBERON:0000178	52.56	silver quality
muscle of leg	UBERON:0001383	51.34	gold quality
monocyte	CL:0000576	51.27	silver quality
prefrontal cortex	UBERON:0000451	50.60	gold quality
liver	UBERON:0002107	50.46	gold quality
adrenal gland	UBERON:0002369	50.38	gold quality
right adrenal gland cortex	UBERON:0035827	49.90	gold quality
stomach	UBERON:0000945	49.83	gold quality
vermiform appendix	UBERON:0001154	49.67	gold quality
right adrenal gland	UBERON:0001233	49.14	gold quality
kidney	UBERON:0002113	49.07	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.