ANKH-AS1

Summary

ANKH-AS1 (ANKH antisense RNA 1, HGNC:59005) is a long non-coding RNA gene on chromosome 5p15.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:59005
Approved symbol	ANKH-AS1
Name	ANKH antisense RNA 1
Location	5p15.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000286970
Ensembl biotype	lncRNA
Entrez	124900944

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000654896, ENST00000659482

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000654896 — 2 exons

Exon	Start	End
ENSE00003866589	14729979	14734258
ENSE00003872461	14728587	14729015

Expression profiles

Bgee: expression breadth broad, 80 present calls, max score 76.74.

Top tissues by expression

80 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	76.74	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	69.63	gold quality
sural nerve	UBERON:0015488	67.21	silver quality
substantia nigra	UBERON:0002038	65.07	gold quality
skeletal muscle tissue	UBERON:0001134	63.70	gold quality
corpus callosum	UBERON:0002336	61.45	gold quality
colonic epithelium	UBERON:0000397	61.34	silver quality
tonsil	UBERON:0002372	60.94	silver quality
liver	UBERON:0002107	60.52	gold quality
myometrium	UBERON:0001296	60.32	silver quality
adrenal gland	UBERON:0002369	60.18	silver quality
prefrontal cortex	UBERON:0000451	59.22	gold quality
Ammon’s horn	UBERON:0001954	57.83	gold quality
thoracic mammary gland	UBERON:0005200	57.49	silver quality
primary visual cortex	UBERON:0002436	57.46	gold quality
putamen	UBERON:0001874	57.12	gold quality
hindlimb stylopod muscle	UBERON:0004252	55.99	gold quality
temporal lobe	UBERON:0001871	55.39	gold quality
ovary	UBERON:0000992	55.37	silver quality
amygdala	UBERON:0001876	55.33	gold quality
right lobe of liver	UBERON:0001114	55.01	gold quality
frontal cortex	UBERON:0001870	54.31	gold quality
hypothalamus	UBERON:0001898	53.09	gold quality
muscle of leg	UBERON:0001383	53.05	gold quality
brain	UBERON:0000955	52.45	gold quality
cerebral cortex	UBERON:0000956	52.37	gold quality
Brodmann (1909) area 9	UBERON:0013540	52.12	gold quality
caudate nucleus	UBERON:0001873	50.73	gold quality
multicellular organism	UBERON:0000468	50.64	gold quality
superior frontal gyrus	UBERON:0002661	50.46	gold quality

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.