ANKRD24

Summary

ANKRD24 (ankyrin repeat domain 24, HGNC:29424) is a protein-coding gene on chromosome 19p13.3, encoding Ankyrin repeat domain-containing protein 24 (Q8TF21). Component of the stereocilia rootlet in hair cells of inner ear.

Predicted to enable actin binding activity. Predicted to be involved in auditory receptor cell stereocilium organization and sensory perception of sound. Predicted to be located in plasma membrane. Predicted to be part of stereocilium.

Source: NCBI Gene 170961 — RefSeq curated summary.

At a glance

• Gene–disease (curated): sensorineural hearing loss disorder (Limited, GenCC)
• GWAS associations: 1
• Clinical variants (ClinVar): 253 total — 5 pathogenic, 2 likely-pathogenic
• MANE Select transcript: NM_001393985

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:29424
Approved symbol	ANKRD24
Name	ankyrin repeat domain 24
Location	19p13.3
Locus type	gene with protein product
Status	Approved
Aliases	KIAA1981
Ensembl gene	ENSG00000089847
Ensembl biotype	protein_coding
OMIM	620234
Entrez	170961

Gene structure

Transcript identifiers

Ensembl transcripts: 16 — 14 protein_coding, 1 protein_coding_CDS_not_defined, 1 nonsense_mediated_decay

ENST00000262970, ENST00000318934, ENST00000595096, ENST00000595928, ENST00000597689, ENST00000600132, ENST00000870288, ENST00000870289, ENST00000966466, ENST00000966467, ENST00000966468, ENST00000966469, ENST00000966470, ENST00000966471, ENST00000966472, ENST00000966473

RefSeq mRNA: 7 — MANE Select: NM_001393985 NM_001393552, NM_001393553, NM_001393555, NM_001393556, NM_001393557, NM_001393985, NM_133475

CCDS: CCDS45925

Canonical transcript exons

ENST00000318934 — 22 exons

Exon	Start	End
ENSE00000664023	4208764	4208801
ENSE00000868786	4207781	4207968
ENSE00001208534	4216550	4218163
ENSE00001343014	4202869	4202926
ENSE00001343016	4202026	4202090
ENSE00001557211	4222670	4222795
ENSE00001603222	4224428	4224814
ENSE00001623498	4219591	4219758
ENSE00001651351	4199683	4199769
ENSE00001714355	4200083	4200171
ENSE00001789746	4224127	4224192
ENSE00001795414	4199875	4200005
ENSE00002237883	4186390	4186461
ENSE00003526767	4215978	4216050
ENSE00003541300	4210058	4210138
ENSE00003545894	4212600	4212698
ENSE00003547520	4212475	4212513
ENSE00003603951	4216284	4216402
ENSE00003640141	4207501	4207607
ENSE00003660805	4207242	4207312
ENSE00003678930	4210265	4210372
ENSE00003930003	4182689	4182740

Expression profiles

Bgee: expression breadth ubiquitous, 159 present calls, max score 89.36.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.4997 / max 28.7072, expressed in 159 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
173297	0.4010	143
173296	0.0987	53

Top tissues by expression

243 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right frontal lobe	UBERON:0002810	89.36	gold quality
Brodmann (1909) area 9	UBERON:0013540	89.15	gold quality
anterior cingulate cortex	UBERON:0009835	86.67	gold quality
prefrontal cortex	UBERON:0000451	86.12	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	85.70	gold quality
neocortex	UBERON:0001950	82.79	gold quality
frontal cortex	UBERON:0001870	82.65	gold quality
right lobe of liver	UBERON:0001114	81.04	gold quality
sural nerve	UBERON:0015488	80.45	gold quality
right testis	UBERON:0004534	79.63	gold quality
cerebral cortex	UBERON:0000956	79.51	gold quality
left testis	UBERON:0004533	78.92	gold quality
cortical plate	UBERON:0005343	78.12	gold quality
caudate nucleus	UBERON:0001873	76.98	gold quality
amygdala	UBERON:0001876	76.86	gold quality
putamen	UBERON:0001874	76.83	gold quality
forebrain	UBERON:0001890	76.35	gold quality
nucleus accumbens	UBERON:0001882	75.82	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.80	gold quality
testis	UBERON:0000473	75.79	gold quality
primary visual cortex	UBERON:0002436	75.01	gold quality
hypothalamus	UBERON:0001898	74.34	gold quality
adenohypophysis	UBERON:0002196	74.25	gold quality
brain	UBERON:0000955	74.15	gold quality
buccal mucosa cell	CL:0002336	72.72	silver quality
right adrenal gland	UBERON:0001233	72.53	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	72.47	gold quality
pituitary gland	UBERON:0000007	71.75	gold quality
left adrenal gland	UBERON:0001234	71.74	gold quality
left adrenal gland cortex	UBERON:0035825	71.71	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.57

Regulation

Is transcription factor: no

miRNA regulators (miRDB)

18 targeting ANKRD24, top 30 by miRDB confidence (max_score; target_count = how many genes the miRNA targets in total — lower means more specific):

miRNA	Max score	Avg score	miRNA target_count
HSA-MIR-4534	99.99	66.58	1907
HSA-MIR-5698	99.97	68.49	2029
HSA-MIR-128-3P	99.95	71.17	2484
HSA-MIR-216A-3P	99.95	71.19	2505
HSA-MIR-6783-3P	99.89	67.92	2059
HSA-MIR-1343-3P	99.89	66.78	1815
HSA-MIR-92A-2-5P	99.75	67.01	2164
HSA-MIR-4480	99.42	66.02	735
HSA-MIR-4786-3P	99.36	68.35	1390
HSA-MIR-4764-5P	98.88	65.53	894
HSA-MIR-7843-3P	98.31	67.94	803
HSA-MIR-637	97.91	64.05	1517
HSA-MIR-7154-3P	97.65	65.02	985
HSA-MIR-6895-5P	97.05	64.96	522
HSA-MIR-7847-3P	96.63	64.58	952
HSA-MIR-2861	95.24	65.47	1056
HSA-MIR-1296-5P	93.94	67.71	305
HSA-MIR-6853-5P	93.94	61.88	114

Literature-anchored findings (GeneRIF, showing 1)

• ANKRD24 organizes TRIOBP to reinforce stereocilia insertion points. (PMID:35175278)

Cross-species orthologs

3 orthologs

Organism	Symbol	Gene ID
danio_rerio	ankrd24	ENSDARG00000062103
mus_musculus	Ankrd24	ENSMUSG00000054708
rattus_norvegicus	Ankrd24	ENSRNOG00000006759

Paralogs (2): ASB2 (ENSG00000100628), UACA (ENSG00000137831)

Protein

Protein identifiers

Ankyrin repeat domain-containing protein 24 — Q8TF21 (reviewed: Q8TF21)

All UniProt accessions (3): Q8TF21, M0QZ18, M0R0N9

UniProt curated annotations — full annotation on UniProt →

Function. Component of the stereocilia rootlet in hair cells of inner ear. Bridges the apical plasma membrane with the lower rootlet and maintains normal distribution of TRIOBP, thereby reinforcing stereocilia insertion points and organizing rootlets for hearing with long-term resilience.

Subunit / interactions. Homodimer. Interacts (via C-terminal domain) with TRIOBP (via C-terminal domain) isoform 4; recruits TRIOBP isoform 4 to stereocilia rootlets.

Subcellular location. Cell membrane. Cell projection. Stereocilium.

Isoforms (2)

UniProt ID	Names	Canonical?
Q8TF21-1	1	yes
Q8TF21-2	2

RefSeq proteins (7): NP_001380481, NP_001380482, NP_001380484, NP_001380485, NP_001380486, NP_001380914, NP_597732 (=MANE)

Domains & families (InterPro)

ID	Name	Type
IPR002110	Ankyrin_rpt	Repeat
IPR036770	Ankyrin_rpt-contain_sf	Homologous_superfamily
IPR042420	RAI14/UACA	Family

Pfam: PF00023, PF12796

UniProt features (17 total): repeat 5, sequence variant 4, region of interest 3, coiled-coil region 2, chain 1, compositionally biased region 1, splice variant 1

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Model	pLDDT	Fraction very-high
AF-Q8TF21-F1	70.30	0.30

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 110 (showing top): GOBP_EPITHELIUM_DEVELOPMENT, GOBP_SENSORY_PERCEPTION_OF_MECHANICAL_STIMULUS, GOBP_NEUROGENESIS, GOBP_EPIDERMAL_CELL_DIFFERENTIATION, GOBP_ANIMAL_ORGAN_MORPHOGENESIS, GOBP_EAR_DEVELOPMENT, GOBP_EMBRYONIC_ORGAN_MORPHOGENESIS, GOBP_EAR_MORPHOGENESIS, GOBP_EPIDERMIS_DEVELOPMENT, GOBP_AUDITORY_RECEPTOR_CELL_DEVELOPMENT, GOBP_MECHANORECEPTOR_DIFFERENTIATION, GOBP_HAIR_CELL_DIFFERENTIATION, GOBP_SENSORY_PERCEPTION, GOMF_ACTIN_BINDING, GOCC_NEURON_PROJECTION

GO Biological Process (2): sensory perception of sound (GO:0007605), auditory receptor cell stereocilium organization (GO:0060088)

GO Molecular Function (2): actin binding (GO:0003779), protein binding (GO:0005515)

GO Cellular Component (4): plasma membrane (GO:0005886), stereocilium (GO:0032420), membrane (GO:0016020), cell projection (GO:0042995)

GO top-level categories

Rollup of top GO terms by namespace:

Category	Terms
cellular anatomical structure	2
sensory perception of mechanical stimulus	1
auditory receptor cell morphogenesis	1
inner ear receptor cell stereocilium organization	1
cytoskeletal protein binding	1
binding	1
membrane	1
cell periphery	1
stereocilium bundle	1
neuron projection	1
actin-based cell projection	1

Protein interactions and networks

STRING

1206 interactions, top by confidence (×1000):

Protein A	Protein B	Partner UniProt	Score
ANKRD24	C1QTNF4	Q9BXJ3	493
ANKRD24	GRXCR1	A8MXD5	453
ANKRD24	GNA15	P30679	380
ANKRD24	CCDC184	Q52MB2	379
ANKRD24	PWWP2B	Q6NUJ5	370
ANKRD24	CENPL	Q8N0S6	362
ANKRD24	TEC	P42680	359
ANKRD24	SLF1	Q9BQI6	358
ANKRD24	RASL11A	Q6T310	357
ANKRD24	FBXW4	P57775	350
ANKRD24	CEACAM19	Q7Z692	346
ANKRD24	GIPC3	Q8TF64	345
ANKRD24	RFWD3	Q6PCD5	336
ANKRD24	MAP6	Q96JE9	331
ANKRD24	NEMF	O60524	330

IntAct

12 interactions, top by confidence:

A	B	Type	Score
Dlg4	ANKRD24	psi-mi:“MI:0407”(direct interaction)	0.440
ANKRD24	TSC1	psi-mi:“MI:0915”(physical association)	0.370
NFKB1	NFKB1	psi-mi:“MI:0914”(association)	0.350
M		psi-mi:“MI:0914”(association)	0.350
PACSIN1	ANKRD24	psi-mi:“MI:0915”(physical association)	0.000
NRIP1	ANKRD24	psi-mi:“MI:0915”(physical association)	0.000
PCNT	ANKRD24	psi-mi:“MI:0915”(physical association)	0.000
ANKRD24	UNC119	psi-mi:“MI:0915”(physical association)	0.000
ANKRD24	EEF1A1	psi-mi:“MI:0915”(physical association)	0.000
ANKRD24	RIF1	psi-mi:“MI:0915”(physical association)	0.000

BioGRID (9): ANKRD24 (Affinity Capture-RNA), EEF1A1 (Two-hybrid), LRIF1 (Two-hybrid), UNC119 (Two-hybrid), ANKRD24 (Two-hybrid), ANKRD24 (Two-hybrid), ANKRD24 (Two-hybrid), ANKRD24 (Cross-Linking-MS (XL-MS)), ANKRD24 (Two-hybrid)

ESM2 similar proteins: A0A140LIT1, A0A1B0GVG4, A0JNH6, A1A5D9, A6NC98, A6NGB0, A6NJZ7, A6NNM3, F6XLV1, O15049, O54887, P0C7N4, P58660, P60531, Q0D2H9, Q0P5D1, Q2KJ21, Q2TAC2, Q3LUD3, Q3T1I3, Q3TMW1, Q3V0F0, Q4QRL3, Q5JTB6, Q5RD60, Q66HR5, Q6NSJ2, Q6PHN1, Q6QZQ4, Q80VM7, Q8BP01, Q8C7U1, Q8CB62, Q8CGU1, Q8CHW5, Q8K2I2, Q8N137, Q8N283, Q8N6Y0, Q8R370

Diamond homologs: Q5U312, Q80VM7, Q8CGB3, Q8N283, Q8TF21, Q9EP71, Q9P0K7, Q8HYY4, Q9BZF9, Q9GL21, Q0VCS9, Q8IV38

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

253 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	5
Likely pathogenic	2
Uncertain significance	222
Likely benign	14
Benign	0

Top pathogenic / likely-pathogenic (7)

Variant ID	HGVS	Classification
1340547	GRCh37/hg19 19p13.3(chr19:3501624-5357124)x1	Pathogenic
4682958	GRCh37/hg19 19p13.3(chr19:3134687-5513059)x3	Pathogenic
59083	GRCh38/hg38 19p13.3(chr19:4008560-4763159)x3	Pathogenic
60071	GRCh38/hg38 19p13.3(chr19:3554635-4690965)x1	Pathogenic
625734	GRCh37/hg19 19p13.3(chr19:3076808-4796782)	Pathogenic
155547	GRCh38/hg38 19p13.3(chr19:3788727-5147354)x1	Likely pathogenic
4796690	NM_001393985.1(ANKRD24):c.1934_1937del (p.Thr645fs)	Likely pathogenic

SpliceAI

3515 predictions. Top by Δscore:

Variant	Effect	Δscore
19:4183473:ACCAG:A	donor_gain	1.0000
19:4186460:AGGT:A	donor_loss	1.0000
19:4186461:GGTG:G	donor_loss	1.0000
19:4186463:T:G	donor_loss	1.0000
19:4199874:GA:G	acceptor_gain	1.0000
19:4200004:GC:G	donor_gain	1.0000
19:4200006:G:GG	donor_gain	1.0000
19:4200169:C:T	donor_gain	1.0000
19:4207966:GCG:G	donor_gain	1.0000
19:4208760:CCA:C	acceptor_loss	1.0000
19:4208762:A:AG	acceptor_gain	1.0000
19:4208763:G:GA	acceptor_gain	1.0000
19:4208763:GCC:G	acceptor_gain	1.0000
19:4210054:CCAG:C	acceptor_loss	1.0000
19:4210055:CAG:C	acceptor_loss	1.0000
19:4210056:A:AG	acceptor_gain	1.0000
19:4210056:A:AT	acceptor_loss	1.0000
19:4210057:G:A	acceptor_loss	1.0000
19:4210057:G:GA	acceptor_gain	1.0000
19:4210057:GA:G	acceptor_gain	1.0000
19:4210057:GAA:G	acceptor_gain	1.0000
19:4210057:GAAC:G	acceptor_gain	1.0000
19:4210057:GAACT:G	acceptor_gain	1.0000
19:4210135:GCCG:G	donor_gain	1.0000
19:4210136:CCGG:C	donor_loss	1.0000
19:4210137:CGG:C	donor_loss	1.0000
19:4210139:G:GA	donor_loss	1.0000
19:4210140:T:A	donor_loss	1.0000
19:4210355:G:GT	donor_gain	1.0000
19:4210356:A:T	donor_gain	1.0000

AlphaMissense

7345 scored. Top likely-pathogenic:

Variant	Protein change	am_pathogenicity
19:4200097:C:A	A90D	0.997
19:4202044:T:C	L121P	0.997
19:4200085:T:C	F86S	0.996
19:4202050:C:A	A123D	0.996
19:4202083:T:C	L134P	0.996
19:4222680:T:C	L1061P	0.996
19:4199914:G:C	A55P	0.995
19:4202047:C:A	A122D	0.995
19:4202894:A:T	D145V	0.995
19:4219598:G:C	R1004P	0.995
19:4224176:T:C	L1116P	0.995
19:4199906:T:C	L52P	0.994
19:4200091:T:C	L88P	0.994
19:4200130:T:G	M101R	0.994
19:4202049:G:C	A123P	0.994
19:4202893:G:C	D145H	0.994
19:4207275:T:A	L167H	0.994
19:4207529:C:A	A189D	0.994
19:4219603:G:C	A1006P	0.994
19:4222694:T:C	F1066L	0.994
19:4222696:C:A	F1066L	0.994
19:4222696:C:G	F1066L	0.994
19:4200001:T:C	S84P	0.993
19:4200094:C:A	A89E	0.993
19:4200130:T:A	M101K	0.993
19:4202912:C:A	A151D	0.993
19:4207528:G:C	A189P	0.993
19:4210299:T:C	L329P	0.993
19:4202893:G:T	D145Y	0.992
19:4218158:T:C	F1000L	0.992

dbSNP variants (sampled 300 via entrez): RS1000061334 (19:4195429 A>G), RS1000182360 (19:4191071 G>A,T), RS1000247402 (19:4192008 C>G), RS1000302634 (19:4195615 G>A), RS1000312816 (19:4185614 G>A), RS1000323873 (19:4185286 G>A), RS1000368925 (19:4221520 G>A), RS1000521593 (19:4200728 C>T), RS1000579900 (19:4193422 C>T), RS1000628960 (19:4196367 T>C), RS1000645787 (19:4190732 C>T), RS1000660100 (19:4186528 G>A), RS1000710552 (19:4186242 A>C,G), RS1000738090 (19:4202582 T>C), RS1000758502 (19:4196976 G>T)

Disease associations

OMIM: gene MIM:620234 | disease phenotypes:

GenCC curated gene-disease

Disease	Classification	Inheritance
sensorineural hearing loss disorder	Limited	Autosomal recessive

Mondo (2): primary amenorrhea (MONDO:1060208), sensorineural hearing loss disorder (MONDO:0020678)

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

1 associations (top):

Study	Trait	p-value
GCST011741_61	LDL cholesterol levels in HIV infection	2.000000e-06

EFO canonical traits (1, from GWAS)

EFO ID	Trait name
EFO:0004611	low density lipoprotein cholesterol measurement

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 1 entry (VIP=true, CPIC=false)

CTD chemical–gene interactions

30 total (human), top 30 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
Benzo(a)pyrene	affects methylation, decreases expression	2
Cisplatin	affects expression, affects cotreatment, increases expression	2
aristolochic acid I	increases expression	1
bisphenol F	affects cotreatment, increases expression	1
fluorene-9-bisphenol	decreases expression	1
sotorasib	affects cotreatment, decreases expression	1
ethyl-p-hydroxybenzoate	decreases expression	1
benzo(e)pyrene	increases methylation	1
ferrous chloride	decreases expression	1
di-n-butylphosphoric acid	affects expression	1
CGP 52608	affects binding, increases reaction	1
abrine	increases expression	1
jinfukang	affects cotreatment, increases expression	1
trametinib	affects cotreatment, decreases expression	1
NVP-BKM120	affects cotreatment, decreases expression	1
Decitabine	affects expression	1
Sunitinib	increases expression	1
Arsenic	affects methylation	1
Dexamethasone	increases expression, affects cotreatment	1
Estradiol	decreases expression	1
Indomethacin	affects cotreatment, increases expression	1
Methapyrilene	increases methylation	1
Rotenone	decreases expression	1
Smoke	decreases expression	1
Tobacco Smoke Pollution	decreases expression	1
Valproic Acid	increases methylation	1
1-Methyl-3-isobutylxanthine	affects cotreatment, increases expression	1
1-Methyl-4-phenylpyridinium	increases expression	1
Okadaic Acid	decreases expression	1
S-Nitrosoglutathione	increases expression	1

Clinical trials (associated diseases)

90 trials via MONDO — disease-level, not drug-specific.

Trial	Phase	Status	Title
NCT01655212	PHASE3	TERMINATED	Congenital Cytomegalovirus: Efficacy of Antiviral Treatment in a Randomized Controlled Trial
NCT02005822	PHASE3	COMPLETED	Congenital Cytomegalovirus: Efficacy of Antiviral Treatment
NCT03374514	PHASE3	UNKNOWN	Cochlear Electrical Impedance and the Effect of Topical Dexamethasone on Cochlear Implant Surgery
NCT02497690	PHASE2	COMPLETED	Effectiveness of Therapy Via Telemedicine Following Cochlear Implants
NCT03107871	PHASE2	ACTIVE_NOT_RECRUITING	Randomized Controlled Trial of Valganciclovir for Cytomegalovirus Infected Hearing Impaired Infants
NCT04120116	PHASE2	COMPLETED	FX-322 in Adults With Stable Sensorineural Hearing Loss
NCT05061758	PHASE2	WITHDRAWN	A Trial of LY3056480 in Patients With SNLH
NCT07364747	PHASE2	RECRUITING	Protective Effect of Acetylcysteine Against Cisplatinum-Induced Ototoxicity: A Randomized Controlled Trial
NCT02259595	PHASE1	COMPLETED	Study to Determine the Safety, Tolerability, and Pharmacokinetic Profile of HPN-07 and HPN-07 Plus NAC
NCT02693704	PHASE2/PHASE3	COMPLETED	Evaluation of a Binaural Spatialization Method for Hearing Aids
NCT02882477	PHASE2/PHASE3	UNKNOWN	Treatment of Wolfram Syndrome Type 2 With the Chelator Deferiprone and Incretin Based Therapy
NCT01267994	PHASE1/PHASE2	COMPLETED	A Clinical Trial of Anakinra for Steroid-Resistant Autoimmune Inner Ear Disease
NCT01902914	PHASE1/PHASE2	UNKNOWN	Effectiveness of P02 Digital Hearing Aids
NCT02038972	PHASE1/PHASE2	COMPLETED	Safety of Autologous Stem Cell Infusion for Children With Acquired Hearing Loss
NCT02616172	PHASE1/PHASE2	SUSPENDED	Autologous Bone Marrow Harvest and Transplant for Sensorineural Hearing Loss
NCT03616223	PHASE1/PHASE2	COMPLETED	FX-322 in Sensorineural Hearing Loss
NCT04129775	PHASE1/PHASE2	COMPLETED	OTO-413 in Subjects With Speech-in-Noise Hearing Impairment
NCT04462198	PHASE1/PHASE2	COMPLETED	Phase I/IIa Study Evaluating Safety and Efficacy of an Intratympanic Dose of PIPE-505 in Subjects With Hearing Loss
NCT07032038	PHASE1/PHASE2	NOT_YET_RECRUITING	First In Human Randomised Trial of Rincell-1 in Adults With a Cochlear Implant
NCT06025097	EARLY_PHASE1	COMPLETED	Intra-Tympanic Steroid With PRP Combination in Sensorineural Hearing Loss and Tinnitus.
NCT06707389	EARLY_PHASE1	NOT_YET_RECRUITING	Autologous Blood Monocyte Vesicles for the Treatment of Sudden Deafness
NCT07472023	EARLY_PHASE1	ENROLLING_BY_INVITATION	Regenerative Medicine and Stem Cell-Based Interventions for Inner Ear Trauma, Tinnitus, and Sensorineural Hearing Loss
NCT00023036	Not specified	COMPLETED	Clinical and Genetic Analysis of Enlarged Vestibular Aqueducts
NCT00023049	Not specified	COMPLETED	Genetic Analysis of Hereditary Disorders of Hearing and Balance
NCT00261768	Not specified	COMPLETED	Efficacy of Digital Noise Reduction Strategies: A Hearing Aid Trial
NCT00589511	Not specified	COMPLETED	Nucleus Freedom Cochlear Implant System Pediatric Post-approval Study
NCT00678899	Not specified	COMPLETED	Evaluation of the Nucleus Hybrid™ L24 Cochlear Implant System
NCT00787189	Not specified	COMPLETED	Study of Low Level Laser Therapy and Word Recognition in Hearing Impaired Individuals
NCT01184248	Not specified	COMPLETED	The Effect of Sound Stimulation on Pure-tone Hearing Threshold
NCT01434446	Not specified	COMPLETED	The Effect of Sound Stimulation on Hearing Ability
NCT01749592	Not specified	COMPLETED	Single-sided Deafness and Cochlear Implants
NCT01781039	Not specified	COMPLETED	Investigation of Anatomical Correlates of Speech Discrimination
NCT02082431	Not specified	COMPLETED	Determine the Incidence of Long QT Amongst a Large Cohort of Subjects Diagnosed With Unilateral or Bilateral Sensorineural Hearing Loss.
NCT02093806	Not specified	UNKNOWN	Clinical Applications of Round Window Imaging Anatomy in Cochlear Implant Surgery
NCT02252601	Not specified	UNKNOWN	Evaluation of the High Frequency Digit Triplet Test in Cystic Fibrosis
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