ANKRD34C-AS1

Summary

ANKRD34C-AS1 (ANKRD34C antisense RNA 1, HGNC:48618) is a long non-coding RNA gene on chromosome 15q25.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48618
Approved symbol	ANKRD34C-AS1
Name	ANKRD34C antisense RNA 1
Location	15q25.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259234
Ensembl biotype	lncRNA
Entrez	729911
RNAcentral	URS000075B35A — lncRNA, 693 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 32 — 32 lncRNA

ENST00000557790, ENST00000558297, ENST00000559225, ENST00000559979, ENST00000560452, ENST00000560533, ENST00000560732, ENST00000560872, ENST00000661423, ENST00000661500, ENST00000668181, ENST00000671603, ENST00000685737, ENST00000686264, ENST00000689461, ENST00000689752, ENST00000692103, ENST00000692216, ENST00000692425, ENST00000701040, ENST00000701559, ENST00000773170, ENST00000773171, ENST00000773172, ENST00000773173, ENST00000773174, ENST00000773175, ENST00000773176, ENST00000773177, ENST00000773178, ENST00000773179, ENST00000773180

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000557790 — 4 exons

Exon	Start	End
ENSE00002542809	79260705	79260846
ENSE00002551415	79260229	79260301
ENSE00002557951	79235301	79236928
ENSE00004137905	79283649	79283945

Expression profiles

Bgee: expression breadth ubiquitous, 104 present calls, max score 77.78.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.5703 / max 34.9190, expressed in 90 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
151177	0.3074	84
151178	0.2629	81

Top tissues by expression

104 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
superior frontal gyrus	UBERON:0002661	77.78	gold quality
prefrontal cortex	UBERON:0000451	76.38	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	74.83	silver quality
frontal cortex	UBERON:0001870	74.80	gold quality
islet of Langerhans	UBERON:0000006	73.09	gold quality
primary visual cortex	UBERON:0002436	73.07	gold quality
nucleus accumbens	UBERON:0001882	72.15	gold quality
right frontal lobe	UBERON:0002810	72.13	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	72.12	gold quality
Brodmann (1909) area 9	UBERON:0013540	72.05	gold quality
cerebral cortex	UBERON:0000956	71.90	gold quality
anterior cingulate cortex	UBERON:0009835	70.22	gold quality
hypothalamus	UBERON:0001898	69.38	gold quality
brain	UBERON:0000955	69.12	gold quality
testis	UBERON:0000473	68.78	gold quality
right hemisphere of cerebellum	UBERON:0014890	68.67	gold quality
cerebellum	UBERON:0002037	68.63	gold quality
cerebellar cortex	UBERON:0002129	68.59	gold quality
cerebellar hemisphere	UBERON:0002245	68.50	gold quality
pituitary gland	UBERON:0000007	68.46	gold quality
caudate nucleus	UBERON:0001873	65.83	gold quality
Ammon’s horn	UBERON:0001954	65.58	gold quality
adenohypophysis	UBERON:0002196	65.39	gold quality
putamen	UBERON:0001874	65.16	gold quality
temporal lobe	UBERON:0001871	63.77	gold quality
amygdala	UBERON:0001876	63.59	gold quality
ventricular zone	UBERON:0003053	61.77	gold quality
ganglionic eminence	UBERON:0004023	61.27	gold quality
cortical plate	UBERON:0005343	60.54	gold quality
pancreas	UBERON:0001264	59.38	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.95

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.