ANKRD44-AS1

Summary

ANKRD44-AS1 (ANKRD44 antisense RNA 1, HGNC:41090) is a long non-coding RNA gene on chromosome 2q33.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41090
Approved symbol	ANKRD44-AS1
Name	ANKRD44 antisense RNA 1
Location	2q33.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000231621
Ensembl biotype	lncRNA
Entrez	101927596
RNAcentral	URS00002E463A — lncRNA, 455 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000449346, ENST00000703007, ENST00000810792, ENST00000810793

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000449346 — 2 exons

Exon	Start	End
ENSE00004208112	197198918	197199512
ENSE00004208113	197197888	197198089

Expression profiles

Bgee: expression breadth ubiquitous, 115 present calls, max score 95.09.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.4150 / max 48.4171, expressed in 85 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
24468	0.4150	85

Top tissues by expression

115 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right uterine tube	UBERON:0001302	95.09	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	90.95	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.55	silver quality
colonic epithelium	UBERON:0000397	80.76	gold quality
fallopian tube	UBERON:0003889	76.68	gold quality
lymph node	UBERON:0000029	74.91	gold quality
granulocyte	CL:0000094	72.98	gold quality
right lung	UBERON:0002167	71.42	gold quality
blood	UBERON:0000178	69.79	gold quality
bone marrow cell	CL:0002092	68.96	silver quality
tonsil	UBERON:0002372	68.65	gold quality
vermiform appendix	UBERON:0001154	67.92	gold quality
endometrium	UBERON:0001295	66.19	gold quality
bone marrow	UBERON:0002371	66.02	gold quality
gall bladder	UBERON:0002110	65.06	gold quality
lung	UBERON:0002048	65.02	gold quality
urinary bladder	UBERON:0001255	64.84	gold quality
endocervix	UBERON:0000458	62.66	gold quality
upper lobe of left lung	UBERON:0008952	62.24	gold quality
muscle tissue	UBERON:0002385	61.69	gold quality
spleen	UBERON:0002106	61.11	gold quality
corpus callosum	UBERON:0002336	61.06	gold quality
leukocyte	CL:0000738	59.96	gold quality
mucosa of transverse colon	UBERON:0004991	59.44	gold quality
smooth muscle tissue	UBERON:0001135	58.55	gold quality
calcaneal tendon	UBERON:0003701	57.66	gold quality
monocyte	CL:0000576	57.21	gold quality
prefrontal cortex	UBERON:0000451	57.14	gold quality
duodenum	UBERON:0002114	56.82	gold quality
placenta	UBERON:0001987	55.90	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-MTAB-10287	yes	25.77
E-ANND-3	yes	9.23

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.