ANKRD44-IT1

Summary

ANKRD44-IT1 (ANKRD44 intronic transcript 1, HGNC:41477) is a long non-coding RNA gene on chromosome 2q33.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41477
Approved symbol	ANKRD44-IT1
Name	ANKRD44 intronic transcript 1
Location	2q33.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000236977
Ensembl biotype	lncRNA
Entrez	101927547
RNAcentral	URS00003BCF80 — lncRNA, 1069 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000428191, ENST00000810708, ENST00000810709, ENST00000810710

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000428191 — 6 exons

Exon	Start	End
ENSE00001631539	197250858	197250992
ENSE00001682000	197296305	197296399
ENSE00001685407	197300963	197301413
ENSE00001718042	197296526	197296572
ENSE00001768935	197299482	197299535
ENSE00001798275	197302233	197302519

Expression profiles

Bgee: expression breadth ubiquitous, 122 present calls, max score 78.71.

Top tissues by expression

218 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	78.71	gold quality
monocyte	CL:0000576	69.63	gold quality
colonic epithelium	UBERON:0000397	67.32	silver quality
buccal mucosa cell	CL:0002336	64.54	gold quality
sural nerve	UBERON:0015488	63.98	silver quality
cortical plate	UBERON:0005343	62.32	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	61.25	gold quality
blood	UBERON:0000178	59.11	gold quality
bone marrow	UBERON:0002371	57.03	gold quality
granulocyte	CL:0000094	56.30	gold quality
corpus callosum	UBERON:0002336	55.35	gold quality
hindlimb stylopod muscle	UBERON:0004252	54.20	gold quality
calcaneal tendon	UBERON:0003701	53.89	silver quality
adrenal tissue	UBERON:0018303	53.38	gold quality
cerebellar vermis	UBERON:0004720	52.54	gold quality
lymph node	UBERON:0000029	52.52	gold quality
tonsil	UBERON:0002372	52.47	silver quality
duodenum	UBERON:0002114	52.40	gold quality
liver	UBERON:0002107	49.79	gold quality
vermiform appendix	UBERON:0001154	49.45	gold quality
tendon	UBERON:0000043	48.77	silver quality
lung	UBERON:0002048	48.74	gold quality
muscle of leg	UBERON:0001383	48.69	gold quality
spleen	UBERON:0002106	48.55	gold quality
islet of Langerhans	UBERON:0000006	48.18	silver quality
small intestine	UBERON:0002108	47.99	gold quality
small intestine Peyer’s patch	UBERON:0003454	47.78	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	47.60	gold quality
right lobe of liver	UBERON:0001114	47.31	gold quality
caecum	UBERON:0001153	47.30	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	8.10

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.