ANKRD52

Summary

ANKRD52 (ankyrin repeat domain 52, HGNC:26614) is a protein-coding gene on chromosome 12q13.3, encoding Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (Q8NB46). Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. It is a selective cancer dependency (DepMap: 13.6% of cell lines).

At a glance

• GWAS associations: 4
• Clinical variants (ClinVar): 119 total — 1 pathogenic
• Druggable target: yes — 1 molecules with ChEMBL bioactivity
• Cancer dependency (DepMap): dependent in 13.6% of screened cell lines
• MANE Select transcript: NM_173595

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:26614
Approved symbol	ANKRD52
Name	ankyrin repeat domain 52
Location	12q13.3
Locus type	gene with protein product
Status	Approved
Aliases	FLJ34236, PP6-ARS-C
Ensembl gene	ENSG00000139645
Ensembl biotype	protein_coding
OMIM	620862
Entrez	283373

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 4 retained_intron, 3 protein_coding_CDS_not_defined, 1 protein_coding

ENST00000267116, ENST00000548081, ENST00000548241, ENST00000551023, ENST00000680026, ENST00000680693, ENST00000680755, ENST00000681390

RefSeq mRNA: 1 — MANE Select: NM_173595 NM_173595

CCDS: CCDS44920

Canonical transcript exons

ENST00000267116 — 28 exons

Exon	Start	End
ENSE00001281512	56237807	56243392
ENSE00001504578	56257015	56257085
ENSE00001504579	56257283	56257361
ENSE00001504580	56257828	56257911
ENSE00001596713	56248023	56248224
ENSE00001602909	56247687	56247774
ENSE00001622231	56244906	56244989
ENSE00001632870	56252175	56252315
ENSE00001641706	56248495	56248566
ENSE00001680720	56245377	56245596
ENSE00001681740	56253004	56253086
ENSE00001683826	56252502	56252570
ENSE00001688791	56253722	56253800
ENSE00001699911	56248759	56248870
ENSE00001702548	56245103	56245190
ENSE00001729191	56253288	56253402
ENSE00001730470	56244652	56244797
ENSE00001746902	56247493	56247610
ENSE00001764567	56252015	56252095
ENSE00001780234	56252780	56252897
ENSE00002302329	56254067	56254279
ENSE00002371690	56258243	56258384
ENSE00003459701	56254578	56254720
ENSE00003475111	56244353	56244435
ENSE00003480316	56243785	56243876
ENSE00003513002	56254865	56254952
ENSE00003629937	56244051	56244133
ENSE00003638967	56255784	56255984

Expression profiles

Bgee: expression breadth ubiquitous, 191 present calls, max score 91.14.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 18.2970 / max 117.4627, expressed in 1800 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
131498	17.6385	1798
131497	0.3411	142
131499	0.3173	164

Top tissues by expression

245 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
stromal cell of endometrium	CL:0002255	91.14	gold quality
lateral nuclear group of thalamus	UBERON:0002736	88.86	silver quality
right adrenal gland	UBERON:0001233	88.74	gold quality
right adrenal gland cortex	UBERON:0035827	88.68	gold quality
substantia nigra pars reticulata	UBERON:0001966	88.53	silver quality
nasal cavity epithelium	UBERON:0005384	88.16	gold quality
adrenal cortex	UBERON:0001235	88.00	gold quality
left adrenal gland cortex	UBERON:0035825	87.96	gold quality
left adrenal gland	UBERON:0001234	87.95	gold quality
upper arm skin	UBERON:0004263	87.40	gold quality
adrenal gland	UBERON:0002369	87.05	gold quality
right hemisphere of cerebellum	UBERON:0014890	86.31	gold quality
gastrocnemius	UBERON:0001388	86.12	gold quality
adrenal tissue	UBERON:0018303	86.02	gold quality
kidney epithelium	UBERON:0004819	86.00	gold quality
muscle of leg	UBERON:0001383	85.84	gold quality
cerebellar cortex	UBERON:0002129	85.70	gold quality
cerebellar hemisphere	UBERON:0002245	85.69	gold quality
cerebellum	UBERON:0002037	85.11	gold quality
islet of Langerhans	UBERON:0000006	84.66	gold quality
apex of heart	UBERON:0002098	84.42	gold quality
cerebellar vermis	UBERON:0004720	84.23	silver quality
granulocyte	CL:0000094	84.11	gold quality
metanephros cortex	UBERON:0010533	83.95	gold quality
hindlimb stylopod muscle	UBERON:0004252	83.79	gold quality
prefrontal cortex	UBERON:0000451	83.65	gold quality
lower esophagus	UBERON:0013473	83.64	gold quality
lower esophagus muscularis layer	UBERON:0035833	83.64	gold quality
body of uterus	UBERON:0009853	83.43	gold quality
ventral tegmental area	UBERON:0002691	83.40	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.49

Regulation

Is transcription factor: no

miRNA regulators (miRDB)

344 targeting ANKRD52, top 30 by miRDB confidence (max_score; target_count = how many genes the miRNA targets in total — lower means more specific):

miRNA	Max score	Avg score	miRNA target_count
HSA-MIR-4747-5P	100.00	67.90	2681
HSA-MIR-5196-5P	100.00	67.98	2761
HSA-MIR-4481	100.00	66.42	1669
HSA-MIR-4262	100.00	73.26	3931
HSA-MIR-4673	100.00	66.64	1490
HSA-MIR-29A-3P	100.00	73.11	1835
HSA-MIR-29B-3P	100.00	73.18	1833
HSA-MIR-29C-3P	100.00	73.15	1833
HSA-MIR-9-5P	100.00	72.28	2361
HSA-MIR-4283	100.00	66.42	2097
HSA-MIR-8485	100.00	77.57	4731
HSA-MIR-4510	100.00	66.60	2050
HSA-MIR-6127	100.00	66.76	2188
HSA-MIR-6798-5P	100.00	65.77	699
HSA-MIR-7110-3P	100.00	73.18	2486
HSA-MIR-6129	100.00	66.46	2080
HSA-MIR-6130	100.00	66.69	2012
HSA-MIR-6133	100.00	66.48	2064
HSA-MIR-574-5P	100.00	66.01	989
HSA-MIR-5692A	100.00	74.40	6850
HSA-MIR-34A-5P	99.99	71.21	1784
HSA-MIR-449A	99.99	71.05	1776
HSA-MIR-6870-5P	99.99	68.55	2115
HSA-MIR-4500	99.99	72.72	2367
HSA-MIR-181A-5P	99.99	72.96	2995
HSA-MIR-181B-5P	99.99	72.97	2996
HSA-MIR-181C-5P	99.99	72.95	2996
HSA-MIR-181D-5P	99.99	73.04	2997
HSA-MIR-4531	99.99	69.70	3181
HSA-MIR-4645-5P	99.98	65.81	1284

Functional genomics

DepMap (CRISPR cell-line fitness): dependent in 13.6% of screened cell lines.

Literature-anchored findings (GeneRIF, showing 3)

• ANKRD52 mediates the PP6-ASK3 interaction and, consequently, ASK3 inactivation under hyperosmotic stress. (PMID:29539411)
• TAZ negatively regulates the novel tumor suppressor ANKRD52 and promotes PAK1 dephosphorylation in lung adenocarcinomas. (PMID:33096142)
• ANKRD52 condensates are not completely colocalized with ASK3 condensates, but they move around and grow while sharing their phase boundaries. (PMID:33649309)

Cross-species orthologs

3 orthologs

Organism	Symbol	Gene ID
danio_rerio	ankrd52a	ENSDARG00000036826
mus_musculus	Ankrd52	ENSMUSG00000014498
rattus_norvegicus	Ankrd52	ENSRNOG00000030597

Paralogs (3): ANKRD44 (ENSG00000065413), ANKRD55 (ENSG00000164512), ANKRD28 (ENSG00000206560)

Protein

Protein identifiers

Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C — Q8NB46 (reviewed: Q8NB46)

Alternative names: Ankyrin repeat domain-containing protein 52

All UniProt accessions (1): Q8NB46

UniProt curated annotations — full annotation on UniProt →

Function. Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates.

Subunit / interactions. Protein phosphatase 6 (PP6) holoenzyme is proposed to be a heterotrimeric complex formed by the catalytic subunit, a SAPS domain-containing subunit (PP6R) and an ankyrin repeat-domain containing regulatory subunit (ARS). Interacts with PPP6R1.

RefSeq proteins (1): NP_775866* (*=MANE)

Domains & families (InterPro)

ID	Name	Type
IPR002110	Ankyrin_rpt	Repeat
IPR036770	Ankyrin_rpt-contain_sf	Homologous_superfamily
IPR050889	Dendritic_Spine_Reg/Scaffold	Family

Pfam: PF00023, PF12796, PF13637

UniProt features (35 total): repeat 28, modified residue 2, sequence conflict 2, chain 1, region of interest 1, compositionally biased region 1

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Model	pLDDT	Fraction very-high
AF-Q8NB46-F1	85.71	0.69

Functional residue map

Curated UniProt residues grouped by drug-discovery relevance — catalytic, ligand-binding, modification, and mutation-validated positions. Source: UniProtKB sequence features.

Post-translational modifications (2): 1028, 1075

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (1): protein binding (GO:0005515)

GO Cellular Component (0):

GO top-level categories

Rollup of top GO terms by namespace:

Category	Terms
binding	1

Protein interactions and networks

STRING

1930 interactions, top by confidence (×1000):

Protein A	Protein B	Partner UniProt	Score
ANKRD52	PPP6C	O00743	838
ANKRD52	PPP6R1	Q9UPN7	683
ANKRD52	PAIP2	Q9BPZ3	671
ANKRD52	EIF3J	O75822	657
ANKRD52	PPP6R2	O75170	657
ANKRD52	SIRT7	Q9NRC8	653
ANKRD52	PPP6R3	Q5H9R7	591
ANKRD52	ZNF609	O15014	573
ANKRD52	MBNL3	Q9NUK0	552
ANKRD52	MBNL2	Q5VZF2	531
ANKRD52	MBNL1	Q9NR56	515
ANKRD52	HIPK3	Q9H422	502
ANKRD52	FAM133B	Q5BKY9	476
ANKRD52	SHPRH	Q149N8	466
ANKRD52	FMNL2	Q96PY5	462

IntAct

92 interactions, top by confidence:

A	B	Type	Score
CDK4	CDKN2C	psi-mi:“MI:0914”(association)	0.970
PPP6R1	PPP6C	psi-mi:“MI:0914”(association)	0.920
PPP6C	ANKRD28	psi-mi:“MI:0914”(association)	0.870
ANKRD28	PPP6C	psi-mi:“MI:0914”(association)	0.870
PPP6R2	PPP6C	psi-mi:“MI:0914”(association)	0.870
HIF1AN	APBA3	psi-mi:“MI:0914”(association)	0.850
ANKRD52	PPP6C	psi-mi:“MI:0914”(association)	0.790
PKN3	ARHGAP10	psi-mi:“MI:0914”(association)	0.680
ANKRD52	PPP6R1	psi-mi:“MI:0914”(association)	0.670
FOXK2	DVL2	psi-mi:“MI:0914”(association)	0.640
HIF1AN	GMDS	psi-mi:“MI:0914”(association)	0.640
USP10	ANKRD28	psi-mi:“MI:0914”(association)	0.610
PLK1	C1orf226	psi-mi:“MI:0914”(association)	0.560
KIF2B	BACH1	psi-mi:“MI:0914”(association)	0.530
ZNF223	PPM1G	psi-mi:“MI:0914”(association)	0.530
ZNF669	LRP4	psi-mi:“MI:0914”(association)	0.530
GREM2	ZZEF1	psi-mi:“MI:0914”(association)	0.530
CPNE5	RAD21	psi-mi:“MI:0914”(association)	0.530
ZNF223	CENPB	psi-mi:“MI:0914”(association)	0.530
MOB1B	PPP6C	psi-mi:“MI:2364”(proximity)	0.480
Ppp6r3	PPP6C	psi-mi:“MI:0914”(association)	0.420
MOB1A	PPP6C	psi-mi:“MI:2364”(proximity)	0.420
Ppp6r3	PPP6C	psi-mi:“MI:2364”(proximity)	0.420

BioGRID (137): ANKRD52 (Affinity Capture-RNA), ANKRD52 (Affinity Capture-RNA), ANKRD52 (Affinity Capture-MS), ANKRD52 (Affinity Capture-MS), ANKRD52 (Proximity Label-MS), ANKRD52 (Affinity Capture-MS), ANKRD52 (Affinity Capture-MS), ANKRD52 (Affinity Capture-MS), ANKRD52 (Affinity Capture-MS), ANKRD52 (Affinity Capture-MS), ANKRD52 (Affinity Capture-MS), ANKRD52 (Affinity Capture-MS), ANKRD52 (Affinity Capture-MS), ANKRD52 (Affinity Capture-MS), ANKRD52 (Affinity Capture-MS)

ESM2 similar proteins: A2AS55, B2RXR6, O15084, O75832, P0C927, Q08DV6, Q0P5B9, Q29RM5, Q2TB02, Q3SX45, Q495B1, Q499M5, Q4V890, Q502K3, Q505D1, Q53RE8, Q5F478, Q5RFS1, Q5U2S6, Q5ZLC8, Q6GPE5, Q6P6B7, Q6P9Z4, Q70X92, Q7T3P8, Q810B6, Q8BTI7, Q8C0T1, Q8C6Y6, Q8K0L0, Q8N8A2, Q8NB46, Q8NI38, Q8WXH4, Q91ZT8, Q96AX9, Q96DX5, Q96NS5, Q96Q27, Q9BSK4

Diamond homologs: A2ARS0, B2RXR6, C7B178, C9JTQ0, P0C927, P19838, Q00PJ3, Q07E43, Q08353, Q21920, Q29RM5, Q2QL84, Q337A0, Q3KP44, Q3SX00, Q3UES3, Q3UUF8, Q4FE45, Q4JHE0, Q4V890, Q502K3, Q5R8C8, Q5ZLC8, Q60J38, Q6KAE5, Q6TNT2, Q76K24, Q7EZ44, Q86W74, Q86WC6, Q8BTI7, Q8BTZ5, Q8C0T1, Q8NB46, Q8VHS5, Q9BSK4, Q9D119, Q9H2K2, Q9N3Q8, Q9Z2G1

SIGNOR signaling

0 interactions.

Enriched among interaction partners

Reactome pathways and GO biological processes over-represented among this gene’s 103 IntAct physical interaction partners (hypergeometric vs the genome-wide background, BH-FDR, gene-set size 15–500, ranked by fold). A functional readout of the neighbourhood — distinct from this gene’s own memberships above, and biased toward well-studied / hub proteins, so read it as themes rather than proof.

GO biological processes:

GO term	Partners	Fold	FDR
autophagosome assembly	5	12.6×	7e-03
protein dephosphorylation	5	12.5×	7e-03
protein phosphorylation	8	6.1×	7e-03

Disease & clinical

Clinical variants and AI predictions

ClinVar

119 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	1
Likely pathogenic	0
Uncertain significance	91
Likely benign	1
Benign	2

Top pathogenic / likely-pathogenic (1)

Variant ID	HGVS	Classification
4280325	NC_000012.12:g.56173943_56407078inv	Pathogenic

SpliceAI

3613 predictions. Top by Δscore:

Variant	Effect	Δscore
12:56243391:ACCT:A	acceptor_loss	1.0000
12:56243393:C:CC	acceptor_gain	1.0000
12:56243393:C:CG	acceptor_loss	1.0000
12:56243780:CCCA:C	donor_loss	1.0000
12:56243782:CACCT:C	donor_loss	1.0000
12:56243783:A:T	donor_loss	1.0000
12:56243784:C:CA	donor_loss	1.0000
12:56243874:GGC:G	acceptor_gain	1.0000
12:56243876:CC:C	acceptor_loss	1.0000
12:56243876:CCT:C	acceptor_gain	1.0000
12:56243877:C:CA	acceptor_loss	1.0000
12:56243877:C:CC	acceptor_gain	1.0000
12:56243878:T:A	acceptor_loss	1.0000
12:56243878:T:C	acceptor_gain	1.0000
12:56243878:T:TC	acceptor_gain	1.0000
12:56244047:TCACA:T	donor_loss	1.0000
12:56244049:A:AC	donor_gain	1.0000
12:56244049:A:C	donor_loss	1.0000
12:56244050:C:CA	donor_gain	1.0000
12:56244050:CA:C	donor_gain	1.0000
12:56244050:CAT:C	donor_gain	1.0000
12:56244050:CATCT:C	donor_gain	1.0000
12:56244129:TGGCC:T	acceptor_gain	1.0000
12:56244130:GGCC:G	acceptor_gain	1.0000
12:56244131:GCC:G	acceptor_gain	1.0000
12:56244132:CC:C	acceptor_gain	1.0000
12:56244132:CCC:C	acceptor_gain	1.0000
12:56244133:CC:C	acceptor_gain	1.0000
12:56244134:C:CA	acceptor_loss	1.0000
12:56244134:C:CC	acceptor_gain	1.0000

AlphaMissense

6998 scored. Top likely-pathogenic:

Variant	Protein change	am_pathogenicity
12:56248091:A:G	L637P	1.000
12:56248091:A:T	L637H	1.000
12:56248190:A:G	L604P	1.000
12:56248508:G:T	P588H	1.000
12:56248565:A:G	L569P	1.000
12:56248781:C:A	G561V	1.000
12:56248790:G:T	A558D	1.000
12:56252514:T:A	D453V	1.000
12:56252547:A:G	L442P	1.000
12:56252558:A:C	C438W	1.000
12:56252560:A:G	C438R	1.000
12:56252789:G:T	A431D	1.000
12:56252792:G:T	A430D	1.000
12:56252803:A:C	C426W	1.000
12:56252804:C:T	C426Y	1.000
12:56252805:A:G	C426R	1.000
12:56252810:C:G	R424P	1.000
12:56252811:G:T	R424S	1.000
12:56252822:T:A	D420V	1.000
12:56252823:C:A	D420Y	1.000
12:56252823:C:G	D420H	1.000
12:56252839:A:C	F414L	1.000
12:56252839:A:T	F414L	1.000
12:56252841:A:G	F414L	1.000
12:56253012:A:G	L392P	1.000
12:56253015:A:G	L391P	1.000
12:56253021:C:G	R389P	1.000
12:56253023:A:C	C388W	1.000
12:56253026:A:C	C387W	1.000
12:56253027:C:T	C387Y	1.000

dbSNP variants (sampled 300 via entrez): RS1000156605 (12:56249079 C>G), RS1000393735 (12:56245525 A>G), RS1000789373 (12:56240517 C>T), RS1000827861 (12:56245915 C>G), RS1000883162 (12:56244632 C>A,T), RS1000925149 (12:56240802 T>C), RS1000937845 (12:56257771 G>C,T), RS1001115092 (12:56250746 A>AG), RS1001285047 (12:56238243 C>T), RS1001344263 (12:56241913 G>A), RS1001349637 (12:56249914 C>T), RS1001400768 (12:56250369 T>G), RS1001540634 (12:56259159 G>A), RS1001661350 (12:56259436 C>T), RS1001738054 (12:56238439 C>A)

Disease associations

OMIM: gene MIM:620862 | disease phenotypes: MIM:618362

GenCC curated gene-disease

Mondo (1): Coffin-Siris syndrome 8 (MONDO:0032702)

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

4 associations (top):

Study	Trait	p-value
GCST007325_254	General risk tolerance (MTAG)	2.000000e-09
GCST010002_217	Refractive error	6.000000e-174
GCST011972_40	Height	8.000000e-52
GCST90090967_20	Height	9.000000e-13

EFO canonical traits (1, from GWAS)

EFO ID	Trait name
EFO:0008579	risk-taking behaviour

Drugs & pharmacology

Drug and pharmacology data

Is drug target: yes

ChEMBL targets (1): CHEMBL4105922 (SINGLE PROTEIN)

Molecules with ChEMBL bioactivity

1 molecules (phase ≥1), by development phase (incl. off-target/promiscuous compounds). Patent mentions across the top 20 by phase: 1,538 (via chembl_molecule»patent_compound — counts attach to the compound, not the gene–compound relationship, so off-target/promiscuous molecules can dominate).

Molecule	Name	Phase	Patents
CHEMBL1232461	MOLIBRESIB	2	1,538

PharmGKB: 1 entry (VIP=true, CPIC=false)

ChEMBL bioactivities

1 potent at pChembl≥5 of 1 total, top 1 by pChembl (potency: 10 = 0.1 nM, 6 = 1 µM).

pChembl	Type	Value	Unit	Molecule
5.70	IC50	2020	nM	MOLIBRESIB

PubChem BioAssay actives

1 with measured affinity, of 8 total; 1 most potent distinct compounds. Largely complementary to BindingDB; screening values are coarse (µM, 4 dp), so sub-nM hits tie at the floor.

Compound	Assay	Type	Value	Unit
2-[(4S)-6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]-N-ethylacetamide	2178746: Inhibition of ANKRD52 (unknown origin) incubated for 1 hr by colloidal coomassie staining based LC-MS/MS analysis	ic50	2.0200	uM

CTD chemical–gene interactions

26 total (human), top 26 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
sodium arsenite	increases expression	2
Smoke	decreases expression, increases abundance	2
aristolochic acid I	increases expression	1
FR900359	decreases phosphorylation	1
dicrotophos	increases expression	1
methylmercuric chloride	increases expression	1
triphenyl phosphate	affects expression	1
arsenite	affects binding, decreases reaction	1
butyraldehyde	decreases expression	1
zinc chromate	decreases expression, increases abundance	1
phenanthrene	decreases expression	1
chromium hexavalent ion	decreases expression, increases abundance	1
perfluoro-n-nonanoic acid	decreases expression	1
corosolic acid	decreases expression	1
2-palmitoylglycerol	increases expression	1
2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine	decreases expression, increases response to substance	1
Temozolomide	decreases expression	1
Leflunomide	decreases expression	1
Air Pollutants	increases abundance, decreases expression	1
Benzo(a)pyrene	increases methylation	1
Ivermectin	decreases expression	1
Valproic Acid	affects expression	1
Asbestos, Serpentine	decreases methylation	1
Asbestos, Crocidolite	decreases methylation	1
Asbestos, Amosite	decreases methylation	1
Okadaic Acid	increases expression	1

ChEMBL screening assays

7 unique, capped per target: 7 binding

Representative assays (with source publication via chembl_document):

Assay ID	Type	Description	Source paper
CHEMBL4012576	Binding	Binding affinity to serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C in human INA-6 cells after 3 hrs by nanoLC-MS/MS method	Ugi Reaction-Derived α-Acyl Aminocarboxamides Bind to Phosphatidylinositol 3-Kinase-Related Kinases, Inhibit HSF1-Dependent Heat Shock Response, and Induce Apoptosis in Multiple Myeloma Cells. — J Med Chem

Cellosaurus cell lines

3 cell lines: 2 cancer cell line, 1 transformed cell line

First 10 cell lines (id-ordered, not curated):

Cellosaurus	Name	Category	Sex
CVCL_B2RM	Abcam HEK293T ANKRD52 KO	Transformed cell line	Female
CVCL_SC58	HAP1 ANKRD52 (-) 1	Cancer cell line	Male
CVCL_SC59	HAP1 ANKRD52 (-) 2	Cancer cell line	Male

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.