ANXA2R-OT1

Summary

ANXA2R-OT1 (ANXA2R overlapping transcript 1, HGNC:48996) is a long non-coding RNA gene on chromosome 5p12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48996
Approved symbol	ANXA2R-OT1
Name	ANXA2R overlapping transcript 1
Location	5p12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000177738
Ensembl biotype	lncRNA
Entrez	648987
RNAcentral	URS000075C48A — lncRNA, 635 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 89 — 89 lncRNA

ENST00000314957, ENST00000499871, ENST00000503152, ENST00000607715, ENST00000654466, ENST00000655830, ENST00000657195, ENST00000659142, ENST00000665537, ENST00000686257, ENST00000689869, ENST00000701039, ENST00000701470, ENST00000702244, ENST00000716688, ENST00000771912, ENST00000771913, ENST00000771914, ENST00000771915, ENST00000771916, ENST00000771917, ENST00000771918, ENST00000771919, ENST00000771920, ENST00000771921, ENST00000771922, ENST00000771923, ENST00000771924, ENST00000771925, ENST00000771926, ENST00000771927, ENST00000771928, ENST00000771929, ENST00000771930, ENST00000771931, ENST00000771932, ENST00000771933, ENST00000771934, ENST00000771935, ENST00000771936, ENST00000771937, ENST00000771938, ENST00000771939, ENST00000771940, ENST00000771941, ENST00000771942, ENST00000771943, ENST00000771944, ENST00000771945, ENST00000771946, ENST00000771947, ENST00000771948, ENST00000771949, ENST00000771950, ENST00000771951, ENST00000771952, ENST00000771953, ENST00000771954, ENST00000771955, ENST00000771956, ENST00000771957, ENST00000771958, ENST00000771959, ENST00000771960, ENST00000771961, ENST00000771962, ENST00000771963, ENST00000771964, ENST00000771965, ENST00000771966, ENST00000771967, ENST00000771968, ENST00000771969, ENST00000771970, ENST00000771971, ENST00000771972, ENST00000771973, ENST00000771974, ENST00000771975, ENST00000771976, ENST00000771977, ENST00000771978, ENST00000772212, ENST00000772213, ENST00000772214, ENST00000772215, ENST00000773207, ENST00000773208, ENST00000773747

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000314957 — 2 exons

Exon	Start	End
ENSE00004135931	43014414	43015150
ENSE00004135938	43017074	43018781

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 80.64.

Top tissues by expression

136 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
quadriceps femoris	UBERON:0001377	80.64	gold quality
granulocyte	CL:0000094	80.57	gold quality
monocyte	CL:0000576	80.44	gold quality
bone marrow	UBERON:0002371	80.39	gold quality
leukocyte	CL:0000738	80.26	gold quality
lymph node	UBERON:0000029	79.69	gold quality
bone marrow cell	CL:0002092	79.32	gold quality
popliteal artery	UBERON:0002250	78.98	gold quality
tibial artery	UBERON:0007610	78.96	gold quality
right coronary artery	UBERON:0001625	78.74	gold quality
descending thoracic aorta	UBERON:0002345	78.72	gold quality
endocervix	UBERON:0000458	78.17	gold quality
spleen	UBERON:0002106	78.10	gold quality
thoracic aorta	UBERON:0001515	78.08	gold quality
ascending aorta	UBERON:0001496	78.03	gold quality
left testis	UBERON:0004533	78.02	gold quality
testis	UBERON:0000473	77.90	gold quality
left coronary artery	UBERON:0001626	77.79	gold quality
right testis	UBERON:0004534	77.74	gold quality
placenta	UBERON:0001987	77.46	gold quality
smooth muscle tissue	UBERON:0001135	77.43	gold quality
skeletal muscle tissue	UBERON:0001134	77.40	gold quality
vermiform appendix	UBERON:0001154	77.37	gold quality
muscle of leg	UBERON:0001383	77.18	gold quality
prostate gland	UBERON:0002367	77.13	gold quality
blood	UBERON:0000178	77.10	gold quality
right lobe of thyroid gland	UBERON:0001119	77.01	gold quality
gastrocnemius	UBERON:0001388	76.94	gold quality
ectocervix	UBERON:0012249	76.84	gold quality
stromal cell of endometrium	CL:0002255	76.63	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.88

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Long Non-Coding RNA LOC648987 Promotes Proliferation and Metastasis of Renal Cell Carcinoma by Regulating Epithelial-Mesenchymal Transition. (PMID:33858283)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.