AP4B1-AS1

Summary

AP4B1-AS1 (AP4B1 antisense RNA 1, HGNC:44114) is a long non-coding RNA gene on chromosome 1p13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:44114
Approved symbol	AP4B1-AS1
Name	AP4B1 antisense RNA 1
Location	1p13.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226167
Ensembl biotype	lncRNA
Entrez	100287722
RNAcentral	URS000036AE88 — lncRNA, 1734 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 16 — 16 lncRNA

ENST00000418238, ENST00000419536, ENST00000429398, ENST00000448199, ENST00000664434, ENST00000702317, ENST00000717022, ENST00000836797, ENST00000836798, ENST00000836799, ENST00000836800, ENST00000836801, ENST00000836802, ENST00000836803, ENST00000836804, ENST00000836805

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000418238 — 2 exons

Exon	Start	End
ENSE00004256624	113814387	113814634
ENSE00004256625	113812579	113812825

Expression profiles

Bgee: expression breadth ubiquitous, 130 present calls, max score 79.30.

FANTOM5 (CAGE): breadth broad, TPM avg 1.6862 / max 47.3639, expressed in 420 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
4725	1.6862	420

Top tissues by expression

130 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	79.30	gold quality
granulocyte	CL:0000094	74.47	gold quality
lymph node	UBERON:0000029	71.13	gold quality
duodenum	UBERON:0002114	70.68	gold quality
right hemisphere of cerebellum	UBERON:0014890	70.67	gold quality
bone marrow	UBERON:0002371	70.40	gold quality
cerebellar hemisphere	UBERON:0002245	70.31	gold quality
cerebellar cortex	UBERON:0002129	70.28	gold quality
body of pancreas	UBERON:0001150	70.27	gold quality
vermiform appendix	UBERON:0001154	70.23	gold quality
cerebellum	UBERON:0002037	70.15	gold quality
endometrium	UBERON:0001295	69.55	gold quality
colonic epithelium	UBERON:0000397	69.01	silver quality
spleen	UBERON:0002106	68.86	gold quality
blood	UBERON:0000178	68.37	gold quality
rectum	UBERON:0001052	68.16	gold quality
monocyte	CL:0000576	67.79	gold quality
cortical plate	UBERON:0005343	67.49	gold quality
leukocyte	CL:0000738	67.40	gold quality
bone marrow cell	CL:0002092	67.27	silver quality
small intestine Peyer’s patch	UBERON:0003454	67.17	gold quality
ganglionic eminence	UBERON:0004023	67.14	gold quality
small intestine	UBERON:0002108	67.12	gold quality
transverse colon	UBERON:0001157	67.09	gold quality
right ovary	UBERON:0002118	66.12	gold quality
left ovary	UBERON:0002119	65.87	gold quality
ovary	UBERON:0000992	65.53	gold quality
intestine	UBERON:0000160	65.52	gold quality
body of stomach	UBERON:0001161	65.49	gold quality
fundus of stomach	UBERON:0001160	65.38	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.06

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.