APBB2-AS1

Summary

APBB2-AS1 (APBB2 antisense RNA 1, HGNC:58763) is a long non-coding RNA gene on chromosome 4p14.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58763
Approved symbol	APBB2-AS1
Name	APBB2 antisense RNA 1
Location	4p14
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000250906
Ensembl biotype	lncRNA
Entrez	143528982

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000513127

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000513127 — 2 exons

Exon	Start	End
ENSE00002043690	40812779	40812857
ENSE00002051938	40825754	40826151

Expression profiles

Bgee: expression breadth ubiquitous, 127 present calls, max score 82.05.

Top tissues by expression

127 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.05	gold quality
cortical plate	UBERON:0005343	74.67	gold quality
right ovary	UBERON:0002118	73.12	gold quality
tibial nerve	UBERON:0001323	73.05	gold quality
corpus callosum	UBERON:0002336	72.46	gold quality
subcutaneous adipose tissue	UBERON:0002190	72.15	gold quality
left ovary	UBERON:0002119	72.12	gold quality
popliteal artery	UBERON:0002250	71.41	gold quality
tibial artery	UBERON:0007610	71.39	gold quality
ovary	UBERON:0000992	71.23	gold quality
right lobe of thyroid gland	UBERON:0001119	70.01	gold quality
bone marrow	UBERON:0002371	70.01	gold quality
thyroid gland	UBERON:0002046	69.87	gold quality
thoracic mammary gland	UBERON:0005200	69.68	gold quality
mucosa of stomach	UBERON:0001199	69.66	gold quality
ascending aorta	UBERON:0001496	69.45	gold quality
left lobe of thyroid gland	UBERON:0001120	69.43	gold quality
adipose tissue	UBERON:0001013	69.19	gold quality
thoracic aorta	UBERON:0001515	68.76	gold quality
ventricular zone	UBERON:0003053	68.30	gold quality
uterine cervix	UBERON:0000002	67.52	gold quality
descending thoracic aorta	UBERON:0002345	67.41	gold quality
skin of leg	UBERON:0001511	67.38	gold quality
endocervix	UBERON:0000458	67.35	gold quality
ganglionic eminence	UBERON:0004023	67.26	gold quality
myometrium	UBERON:0001296	67.03	gold quality
right lung	UBERON:0002167	66.84	gold quality
ectocervix	UBERON:0012249	66.74	gold quality
zone of skin	UBERON:0000014	66.21	gold quality
omental fat pad	UBERON:0010414	65.90	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.32

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.