ARFGEF1-DT

Summary

ARFGEF1-DT (ARFGEF1 divergent transcript, HGNC:55237) is a long non-coding RNA gene on chromosome 8q13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55237
Approved symbol	ARFGEF1-DT
Name	ARFGEF1 divergent transcript
Location	8q13.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	lncDDR, AC021321.1
Ensembl gene	ENSG00000271966
Ensembl biotype	lncRNA
Entrez	102724708
RNAcentral	URS0000A769EB — lncRNA, 2041 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000607397, ENST00000723776, ENST00000723777, ENST00000723778, ENST00000723779, ENST00000723780, ENST00000723781

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000607397 — 1 exons

Exon	Start	End
ENSE00003699357	67343975	67345087

Expression profiles

Bgee: expression breadth ubiquitous, 127 present calls, max score 73.83.

Top tissues by expression

127 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	73.83	silver quality
bone marrow	UBERON:0002371	72.29	gold quality
ganglionic eminence	UBERON:0004023	64.79	gold quality
endometrium	UBERON:0001295	64.07	gold quality
right uterine tube	UBERON:0001302	64.05	gold quality
metanephros cortex	UBERON:0010533	63.87	gold quality
cortical plate	UBERON:0005343	63.54	gold quality
ventricular zone	UBERON:0003053	63.04	gold quality
endocervix	UBERON:0000458	62.35	gold quality
stromal cell of endometrium	CL:0002255	61.79	gold quality
right lobe of thyroid gland	UBERON:0001119	61.77	gold quality
body of uterus	UBERON:0009853	61.56	gold quality
thyroid gland	UBERON:0002046	61.22	gold quality
left lobe of thyroid gland	UBERON:0001120	61.00	gold quality
smooth muscle tissue	UBERON:0001135	60.21	gold quality
cortex of kidney	UBERON:0001225	60.05	gold quality
right coronary artery	UBERON:0001625	60.03	gold quality
descending thoracic aorta	UBERON:0002345	59.85	gold quality
myometrium	UBERON:0001296	59.24	gold quality
urinary bladder	UBERON:0001255	59.10	gold quality
hindlimb stylopod muscle	UBERON:0004252	59.09	gold quality
prostate gland	UBERON:0002367	59.06	gold quality
thoracic aorta	UBERON:0001515	58.88	gold quality
ovary	UBERON:0000992	58.87	gold quality
monocyte	CL:0000576	58.84	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	58.77	gold quality
blood	UBERON:0000178	58.75	gold quality
right ovary	UBERON:0002118	58.74	gold quality
left ovary	UBERON:0002119	58.64	gold quality
ascending aorta	UBERON:0001496	58.62	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.96

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.