ARHGAP22-IT1

Summary

ARHGAP22-IT1 (ARHGAP22 intronic transcript 1, HGNC:42944) is a long non-coding RNA gene on chromosome 10q11.22.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42944
Approved symbol	ARHGAP22-IT1
Name	ARHGAP22 intronic transcript 1
Location	10q11.22
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ35752
Ensembl gene	ENSG00000248682
Ensembl biotype	lncRNA
Entrez	100689073
RNAcentral	URS0000BC4499 — lncRNA, 1143 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000505718, ENST00000819115, ENST00000819116, ENST00000819117, ENST00000819118

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000505718 — 2 exons

Exon	Start	End
ENSE00002046603	48510525	48510939
ENSE00002075345	48511535	48511589

Expression profiles

Bgee: expression breadth broad, 78 present calls, max score 98.49.

Top tissues by expression

182 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	98.49	gold quality
sperm	CL:0000019	95.31	gold quality
right testis	UBERON:0004534	81.29	gold quality
left testis	UBERON:0004533	81.13	gold quality
testis	UBERON:0000473	77.71	gold quality
stromal cell of endometrium	CL:0002255	68.42	gold quality
corpus callosum	UBERON:0002336	68.09	gold quality
hindlimb stylopod muscle	UBERON:0004252	64.09	gold quality
cerebellar vermis	UBERON:0004720	60.61	gold quality
calcaneal tendon	UBERON:0003701	55.67	gold quality
monocyte	CL:0000576	55.29	gold quality
lymph node	UBERON:0000029	54.21	gold quality
thymus	UBERON:0002370	53.76	silver quality
superior vestibular nucleus	UBERON:0007227	51.91	gold quality
urethra	UBERON:0000057	51.85	gold quality
muscle of leg	UBERON:0001383	51.85	gold quality
saphenous vein	UBERON:0007318	51.64	gold quality
dorsal root ganglion	UBERON:0000044	51.60	gold quality
pericardium	UBERON:0002407	51.56	gold quality
uterine cervix	UBERON:0000002	51.47	gold quality
fundus of stomach	UBERON:0001160	51.42	gold quality
medulla oblongata	UBERON:0001896	51.36	gold quality
nipple	UBERON:0002030	51.31	gold quality
trigeminal ganglion	UBERON:0001675	51.26	gold quality
pylorus	UBERON:0001166	51.09	gold quality
superior surface of tongue	UBERON:0007371	51.09	gold quality
cortex of kidney	UBERON:0001225	51.08	gold quality
renal medulla	UBERON:0000362	51.06	gold quality
pons	UBERON:0000988	50.97	gold quality
cardia of stomach	UBERON:0001162	50.86	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.25

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.