ARHGEF18-AS1

Summary

ARHGEF18-AS1 (ARHGEF18 antisense RNA 1, HGNC:55284) is a long non-coding RNA gene on chromosome 19p13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55284
Approved symbol	ARHGEF18-AS1
Name	ARHGEF18 antisense RNA 1
Location	19p13.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000267852
Ensembl biotype	lncRNA
Entrez	118827816
RNAcentral	URS00026A277D — lncRNA, 2765 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000596946, ENST00000795305, ENST00000795306, ENST00000795307, ENST00000795308, ENST00000795309, ENST00000795310

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000596946 — 3 exons

Exon	Start	End
ENSE00003014585	7390522	7390720
ENSE00003050223	7392591	7392707
ENSE00003166044	7394993	7395039

Expression profiles

Bgee: expression breadth ubiquitous, 123 present calls, max score 83.33.

Top tissues by expression

123 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.33	gold quality
bone marrow cell	CL:0002092	74.04	silver quality
bone marrow	UBERON:0002371	72.41	gold quality
ventricular zone	UBERON:0003053	70.64	gold quality
hindlimb stylopod muscle	UBERON:0004252	68.70	gold quality
blood	UBERON:0000178	66.14	gold quality
superior frontal gyrus	UBERON:0002661	65.82	gold quality
lymph node	UBERON:0000029	64.79	gold quality
skeletal muscle tissue	UBERON:0001134	64.33	gold quality
granulocyte	CL:0000094	63.85	gold quality
monocyte	CL:0000576	63.83	gold quality
islet of Langerhans	UBERON:0000006	63.06	gold quality
tonsil	UBERON:0002372	62.50	gold quality
prefrontal cortex	UBERON:0000451	62.25	gold quality
popliteal artery	UBERON:0002250	61.57	gold quality
tibial artery	UBERON:0007610	61.57	gold quality
fallopian tube	UBERON:0003889	61.49	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	61.24	gold quality
smooth muscle tissue	UBERON:0001135	61.07	gold quality
gall bladder	UBERON:0002110	60.70	gold quality
descending thoracic aorta	UBERON:0002345	60.68	gold quality
right ovary	UBERON:0002118	60.01	gold quality
ascending aorta	UBERON:0001496	59.98	gold quality
thoracic aorta	UBERON:0001515	59.86	gold quality
body of uterus	UBERON:0009853	59.72	gold quality
fundus of stomach	UBERON:0001160	59.62	gold quality
left uterine tube	UBERON:0001303	59.43	gold quality
ovary	UBERON:0000992	59.00	gold quality
left coronary artery	UBERON:0001626	58.93	gold quality
muscle of leg	UBERON:0001383	58.27	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.48

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.