ARHGEF2-AS1

Summary

ARHGEF2-AS1 (ARHGEF2 antisense RNA 1, HGNC:40082) is a long non-coding RNA gene on chromosome 1q22.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40082
Approved symbol	ARHGEF2-AS1
Name	ARHGEF2 antisense RNA 1
Location	1q22
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224276
Ensembl biotype	lncRNA
Entrez	107985210
RNAcentral	URS00000EBBA8 — lncRNA, 401 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000415726

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000415726 — 2 exons

Exon	Start	End
ENSE00001618840	155991390	155991510
ENSE00001697651	156001508	156001787

Expression profiles

Bgee: expression breadth ubiquitous, 111 present calls, max score 95.72.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0893 / max 55.4616, expressed in 24 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
5652	0.0893	24

Top tissues by expression

111 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	95.72	gold quality
rectum	UBERON:0001052	76.27	gold quality
right lung	UBERON:0002167	75.46	gold quality
upper lobe of left lung	UBERON:0008952	73.13	gold quality
lung	UBERON:0002048	72.79	gold quality
transverse colon	UBERON:0001157	72.07	gold quality
tibial nerve	UBERON:0001323	70.28	gold quality
body of stomach	UBERON:0001161	69.24	gold quality
colonic epithelium	UBERON:0000397	69.02	gold quality
stomach	UBERON:0000945	67.64	gold quality
sural nerve	UBERON:0015488	67.51	gold quality
left lobe of thyroid gland	UBERON:0001120	67.49	gold quality
thyroid gland	UBERON:0002046	67.24	gold quality
right lobe of thyroid gland	UBERON:0001119	67.07	gold quality
granulocyte	CL:0000094	66.57	gold quality
left testis	UBERON:0004533	66.48	gold quality
testis	UBERON:0000473	66.34	gold quality
right testis	UBERON:0004534	65.65	gold quality
colon	UBERON:0001155	65.11	gold quality
intestine	UBERON:0000160	64.95	gold quality
small intestine	UBERON:0002108	64.36	gold quality
small intestine Peyer’s patch	UBERON:0003454	63.94	gold quality
gall bladder	UBERON:0002110	62.00	gold quality
right uterine tube	UBERON:0001302	61.80	gold quality
bone marrow	UBERON:0002371	60.99	gold quality
duodenum	UBERON:0002114	60.98	gold quality
apex of heart	UBERON:0002098	60.35	gold quality
vermiform appendix	UBERON:0001154	59.29	gold quality
mucosa of stomach	UBERON:0001199	59.20	gold quality
endometrium	UBERON:0001295	59.16	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.81

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.