ARHGEF25-AS1

Summary

ARHGEF25-AS1 (ARHGEF25 antisense RNA 1, HGNC:41260) is a long non-coding RNA gene on chromosome 12q13.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41260
Approved symbol	ARHGEF25-AS1
Name	ARHGEF25 antisense RNA 1
Location	12q13.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224713
Ensembl biotype	lncRNA
Entrez	141369870

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000356672, ENST00000444467, ENST00000593846, ENST00000610219, ENST00000807862

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000356672 — 3 exons

Exon	Start	End
ENSE00001677321	57617761	57618065
ENSE00001678743	57612118	57613709
ENSE00001762668	57615226	57615683

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 95.53.

Top tissues by expression

129 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	95.53	gold quality
apex of heart	UBERON:0002098	82.38	gold quality
muscle layer of sigmoid colon	UBERON:0035805	82.34	gold quality
body of uterus	UBERON:0009853	82.21	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	81.26	gold quality
lower esophagus muscularis layer	UBERON:0035833	81.20	gold quality
lower esophagus	UBERON:0013473	81.17	gold quality
right coronary artery	UBERON:0001625	80.73	gold quality
popliteal artery	UBERON:0002250	80.51	gold quality
tibial artery	UBERON:0007610	80.49	gold quality
myometrium	UBERON:0001296	80.39	gold quality
mucosa of stomach	UBERON:0001199	80.03	gold quality
right hemisphere of cerebellum	UBERON:0014890	79.95	gold quality
left uterine tube	UBERON:0001303	78.55	gold quality
cerebellar hemisphere	UBERON:0002245	78.45	gold quality
cerebellum	UBERON:0002037	78.40	gold quality
cerebellar cortex	UBERON:0002129	78.37	gold quality
thoracic aorta	UBERON:0001515	78.18	gold quality
ascending aorta	UBERON:0001496	78.11	gold quality
descending thoracic aorta	UBERON:0002345	77.95	gold quality
left ovary	UBERON:0002119	77.58	gold quality
left coronary artery	UBERON:0001626	77.54	gold quality
stromal cell of endometrium	CL:0002255	77.53	gold quality
right ovary	UBERON:0002118	77.16	gold quality
ovary	UBERON:0000992	76.44	gold quality
tibial nerve	UBERON:0001323	75.17	gold quality
fundus of stomach	UBERON:0001160	74.41	gold quality
prostate gland	UBERON:0002367	74.21	gold quality
smooth muscle tissue	UBERON:0001135	74.20	gold quality
colon	UBERON:0001155	73.99	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.13

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.