ARHGEF26-AS1

Summary

ARHGEF26-AS1 (ARHGEF26 antisense RNA 1, HGNC:41048) is a long non-coding RNA gene on chromosome 3q25.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41048
Approved symbol	ARHGEF26-AS1
Name	ARHGEF26 antisense RNA 1
Location	3q25.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000243069
Ensembl biotype	lncRNA
Entrez	100507524
RNAcentral	URS000075C1F4 — lncRNA, 2598 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 18 — 16 lncRNA, 2 retained_intron

ENST00000467912, ENST00000479270, ENST00000480639, ENST00000491862, ENST00000597231, ENST00000601822, ENST00000608560, ENST00000610221, ENST00000611093, ENST00000621011, ENST00000630930, ENST00000657305, ENST00000657639, ENST00000659466, ENST00000660955, ENST00000664850, ENST00000687992, ENST00000702004

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000467912 — 4 exons

Exon	Start	End
ENSE00001819330	154030277	154030379
ENSE00001894719	154121072	154121332
ENSE00001916883	154024500	154026642
ENSE00002486175	154119686	154119783

Expression profiles

Bgee: expression breadth ubiquitous, 185 present calls, max score 89.45.

FANTOM5 (CAGE): breadth broad, TPM avg 1.5504 / max 54.2742, expressed in 368 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
45205	0.6385	199
45203	0.3728	131
45204	0.3250	136
45202	0.2141	78

Top tissues by expression

246 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
endothelial cell	CL:0000115	89.45	gold quality
ventral tegmental area	UBERON:0002691	86.67	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.74	gold quality
amygdala	UBERON:0001876	85.56	gold quality
right uterine tube	UBERON:0001302	84.91	gold quality
medulla oblongata	UBERON:0001896	84.67	gold quality
superior vestibular nucleus	UBERON:0007227	84.63	gold quality
nucleus accumbens	UBERON:0001882	84.17	gold quality
temporal lobe	UBERON:0001871	84.14	gold quality
primary visual cortex	UBERON:0002436	83.84	gold quality
entorhinal cortex	UBERON:0002728	83.38	gold quality
occipital lobe	UBERON:0002021	83.25	gold quality
hypothalamus	UBERON:0001898	83.09	gold quality
midbrain	UBERON:0001891	83.07	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.97	gold quality
substantia nigra	UBERON:0002038	82.97	gold quality
lateral globus pallidus	UBERON:0002476	82.73	gold quality
caudate nucleus	UBERON:0001873	82.63	gold quality
sural nerve	UBERON:0015488	82.52	gold quality
Ammon’s horn	UBERON:0001954	82.43	gold quality
anterior cingulate cortex	UBERON:0009835	82.25	gold quality
putamen	UBERON:0001874	81.93	gold quality
Brodmann (1909) area 23	UBERON:0013554	81.49	gold quality
substantia nigra pars compacta	UBERON:0001965	81.39	gold quality
postcentral gyrus	UBERON:0002581	81.08	gold quality
spinal cord	UBERON:0002240	81.01	gold quality
subthalamic nucleus	UBERON:0001906	80.77	gold quality
parietal lobe	UBERON:0001872	80.47	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	80.43	gold quality
tibial nerve	UBERON:0001323	80.32	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	6.16

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.