ARHGEF28-AS2

Summary

ARHGEF28-AS2 (ARHGEF28 antisense RNA 2, HGNC:59067) is a long non-coding RNA gene on chromosome 5q13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:59067
Approved symbol	ARHGEF28-AS2
Name	ARHGEF28 antisense RNA 2
Location	5q13.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000249293
Ensembl biotype	lncRNA
Entrez	144699897

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000506717

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000506717 — 3 exons

Exon	Start	End
ENSE00002035553	73786320	73786491
ENSE00002058909	73780276	73780430
ENSE00002086362	73778039	73778267

Expression profiles

Bgee: expression breadth ubiquitous, 105 present calls, max score 64.95.

Top tissues by expression

105 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
tonsil	UBERON:0002372	64.95	silver quality
lower esophagus mucosa	UBERON:0035834	63.48	gold quality
hindlimb stylopod muscle	UBERON:0004252	63.24	gold quality
tibial nerve	UBERON:0001323	62.44	gold quality
minor salivary gland	UBERON:0001830	58.42	gold quality
saliva-secreting gland	UBERON:0001044	58.34	gold quality
fundus of stomach	UBERON:0001160	57.91	gold quality
left ovary	UBERON:0002119	57.53	gold quality
calcaneal tendon	UBERON:0003701	57.06	gold quality
islet of Langerhans	UBERON:0000006	56.74	gold quality
ovary	UBERON:0000992	56.67	gold quality
ascending aorta	UBERON:0001496	56.00	gold quality
liver	UBERON:0002107	55.94	gold quality
right adrenal gland cortex	UBERON:0035827	55.00	gold quality
thoracic aorta	UBERON:0001515	54.98	gold quality
right lobe of liver	UBERON:0001114	54.37	gold quality
monocyte	CL:0000576	54.08	silver quality
descending thoracic aorta	UBERON:0002345	53.63	gold quality
right ovary	UBERON:0002118	53.55	gold quality
stomach	UBERON:0000945	53.50	gold quality
right adrenal gland	UBERON:0001233	53.37	gold quality
vagina	UBERON:0000996	53.17	gold quality
skin of abdomen	UBERON:0001416	53.13	gold quality
bone marrow	UBERON:0002371	52.91	silver quality
thoracic mammary gland	UBERON:0005200	52.83	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.66	gold quality
esophagus mucosa	UBERON:0002469	52.58	gold quality
adrenal gland	UBERON:0002369	52.28	gold quality
zone of skin	UBERON:0000014	51.96	gold quality
pancreas	UBERON:0001264	51.80	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.10

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.