ARHGEF3-AS1

Summary

ARHGEF3-AS1 (ARHGEF3 antisense RNA 1, HGNC:40083) is a long non-coding RNA gene on chromosome 3p14.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40083
Approved symbol	ARHGEF3-AS1
Name	ARHGEF3 antisense RNA 1
Location	3p14.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000240198
Ensembl biotype	lncRNA
Entrez	100874200
RNAcentral	URS000075F0AD — lncRNA, 500 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000477246, ENST00000495939, ENST00000822764

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000477246 — 3 exons

Exon	Start	End
ENSE00001828245	56940581	56940656
ENSE00001903937	56960580	56960854
ENSE00001926251	56940040	56940177

Expression profiles

Bgee: expression breadth broad, 83 present calls, max score 78.12.

Top tissues by expression

86 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	78.12	gold quality
cerebellar vermis	UBERON:0004720	74.38	gold quality
quadriceps femoris	UBERON:0001377	74.15	gold quality
prefrontal cortex	UBERON:0000451	65.62	gold quality
bone marrow cell	CL:0002092	62.78	silver quality
tonsil	UBERON:0002372	62.41	silver quality
calcaneal tendon	UBERON:0003701	61.44	gold quality
islet of Langerhans	UBERON:0000006	59.90	gold quality
urinary bladder	UBERON:0001255	59.62	silver quality
corpus callosum	UBERON:0002336	59.39	gold quality
thymus	UBERON:0002370	58.14	silver quality
uterine cervix	UBERON:0000002	57.03	silver quality
blood	UBERON:0000178	56.88	gold quality
gall bladder	UBERON:0002110	56.64	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	56.03	gold quality
heart	UBERON:0000948	53.67	gold quality
left testis	UBERON:0004533	53.46	gold quality
gastrocnemius	UBERON:0001388	53.31	gold quality
testis	UBERON:0000473	53.23	gold quality
right testis	UBERON:0004534	53.19	gold quality
popliteal artery	UBERON:0002250	53.07	gold quality
monocyte	CL:0000576	52.97	silver quality
kidney	UBERON:0002113	52.90	gold quality
stomach	UBERON:0000945	52.02	gold quality
endometrium	UBERON:0001295	51.48	gold quality
body of uterus	UBERON:0009853	51.42	gold quality
left adrenal gland cortex	UBERON:0035825	50.35	gold quality
right adrenal gland cortex	UBERON:0035827	50.17	gold quality
heart left ventricle	UBERON:0002084	50.16	gold quality
spleen	UBERON:0002106	50.03	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.47

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.