ARHGEF35-AS1

Summary

ARHGEF35-AS1 (ARHGEF35 antisense RNA 1, HGNC:41292) is a long non-coding RNA gene on chromosome 7q35.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41292
Approved symbol	ARHGEF35-AS1
Name	ARHGEF35 antisense RNA 1
Location	7q35
Locus type	RNA, long non-coding
Status	Approved
Aliases	DDGC
Ensembl gene	ENSG00000244198
Ensembl biotype	lncRNA
Entrez	101928605
RNAcentral	URS00007E3B2E — lncRNA, 990 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 79 — 79 lncRNA

ENST00000460955, ENST00000461471, ENST00000464929, ENST00000474656, ENST00000477797, ENST00000479102, ENST00000480074, ENST00000489077, ENST00000493248, ENST00000498693, ENST00000641566, ENST00000650250, ENST00000663681, ENST00000718476, ENST00000837213, ENST00000837214, ENST00000837215, ENST00000837216, ENST00000837217, ENST00000837218, ENST00000837219, ENST00000837220, ENST00000837221, ENST00000837222, ENST00000837223, ENST00000837224, ENST00000837225, ENST00000837226, ENST00000837227, ENST00000837228, ENST00000837229, ENST00000837230, ENST00000837231, ENST00000837232, ENST00000837233, ENST00000837234, ENST00000837235, ENST00000837236, ENST00000837237, ENST00000837238, ENST00000837239, ENST00000837240, ENST00000837241, ENST00000837242, ENST00000837243, ENST00000837244, ENST00000837245, ENST00000837246, ENST00000837247, ENST00000837248, ENST00000837249, ENST00000837250, ENST00000837251, ENST00000837252, ENST00000837253, ENST00000837254, ENST00000837255, ENST00000837256, ENST00000837257, ENST00000837258, ENST00000837259, ENST00000837260, ENST00000837261, ENST00000837262, ENST00000837263, ENST00000837264, ENST00000837265, ENST00000837266, ENST00000837267, ENST00000837268, ENST00000837269, ENST00000837270, ENST00000837271, ENST00000837272, ENST00000837273, ENST00000837274, ENST00000837275, ENST00000837276, ENST00000837277

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000460955 — 3 exons

Exon	Start	End
ENSE00001810867	144195321	144195701
ENSE00001919030	144280472	144280547
ENSE00002460293	144207693	144207804

Expression profiles

Bgee: expression breadth ubiquitous, 182 present calls, max score 95.82.

Top tissues by expression

250 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left lobe of thyroid gland	UBERON:0001120	95.82	gold quality
right lobe of thyroid gland	UBERON:0001119	95.52	gold quality
thyroid gland	UBERON:0002046	94.86	gold quality
metanephros cortex	UBERON:0010533	90.75	gold quality
tendon of biceps brachii	UBERON:0008188	89.51	gold quality
left ovary	UBERON:0002119	85.46	gold quality
skin of abdomen	UBERON:0001416	85.18	gold quality
right lung	UBERON:0002167	85.00	gold quality
spleen	UBERON:0002106	84.91	gold quality
right uterine tube	UBERON:0001302	84.88	gold quality
right ovary	UBERON:0002118	84.43	gold quality
skin of leg	UBERON:0001511	84.25	gold quality
cortex of kidney	UBERON:0001225	83.67	gold quality
lower esophagus mucosa	UBERON:0035834	83.67	gold quality
granulocyte	CL:0000094	83.49	gold quality
small intestine Peyer’s patch	UBERON:0003454	82.74	gold quality
calcaneal tendon	UBERON:0003701	82.73	gold quality
endocervix	UBERON:0000458	82.45	gold quality
omental fat pad	UBERON:0010414	82.41	gold quality
peritoneum	UBERON:0002358	82.35	gold quality
bone marrow cell	CL:0002092	82.25	gold quality
ectocervix	UBERON:0012249	82.02	gold quality
tendon	UBERON:0000043	81.96	gold quality
sural nerve	UBERON:0015488	81.89	gold quality
ovary	UBERON:0000992	81.73	gold quality
pancreatic ductal cell	CL:0002079	81.62	silver quality
upper lobe of left lung	UBERON:0008952	81.49	gold quality
zone of skin	UBERON:0000014	81.40	gold quality
mucosa of transverse colon	UBERON:0004991	81.26	gold quality
left uterine tube	UBERON:0001303	81.24	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.03

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.