ARHGEF38-IT1

Summary

ARHGEF38-IT1 (ARHGEF38 intronic transcript 1, HGNC:41483) is a long non-coding RNA gene on chromosome 4q24.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41483
Approved symbol	ARHGEF38-IT1
Name	ARHGEF38 intronic transcript 1
Location	4q24
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000249885
Ensembl biotype	lncRNA
Entrez	100874374
RNAcentral	URS00001EFACC — lncRNA, 456 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000512262

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000512262 — 3 exons

Exon	Start	End
ENSE00002039631	105569904	105570238
ENSE00002043403	105563302	105563365
ENSE00002069818	105561591	105561647

Expression profiles

Bgee: expression breadth broad, 76 present calls, max score 70.38.

Top tissues by expression

81 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
tonsil	UBERON:0002372	70.38	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	67.08	gold quality
prostate gland	UBERON:0002367	67.00	gold quality
urinary bladder	UBERON:0001255	65.13	gold quality
colonic epithelium	UBERON:0000397	64.17	silver quality
quadriceps femoris	UBERON:0001377	64.14	gold quality
thoracic mammary gland	UBERON:0005200	63.52	gold quality
cerebellar vermis	UBERON:0004720	63.05	gold quality
minor salivary gland	UBERON:0001830	59.73	gold quality
saliva-secreting gland	UBERON:0001044	59.67	gold quality
skeletal muscle tissue	UBERON:0001134	59.64	silver quality
bone marrow	UBERON:0002371	59.41	silver quality
mucosa of transverse colon	UBERON:0004991	59.39	gold quality
endocervix	UBERON:0000458	58.52	gold quality
thymus	UBERON:0002370	58.30	silver quality
monocyte	CL:0000576	58.23	gold quality
islet of Langerhans	UBERON:0000006	57.31	gold quality
rectum	UBERON:0001052	56.97	gold quality
kidney	UBERON:0002113	56.52	gold quality
gall bladder	UBERON:0002110	55.93	gold quality
adult mammalian kidney	UBERON:0000082	54.96	gold quality
pancreas	UBERON:0001264	54.96	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	54.47	gold quality
body of pancreas	UBERON:0001150	54.25	gold quality
lung	UBERON:0002048	53.89	gold quality
upper lobe of left lung	UBERON:0008952	53.79	gold quality
metanephros cortex	UBERON:0010533	53.42	gold quality
stomach	UBERON:0000945	53.30	gold quality
gastrocnemius	UBERON:0001388	53.28	gold quality
ovary	UBERON:0000992	52.68	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.98

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.