ARHGEF7-AS2

Summary

ARHGEF7-AS2 (ARHGEF7 antisense RNA 2, HGNC:40717) is a long non-coding RNA gene on chromosome 13q34.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40717
Approved symbol	ARHGEF7-AS2
Name	ARHGEF7 antisense RNA 2
Location	13q34
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235875
Ensembl biotype	lncRNA
Entrez	100874238
RNAcentral	URS0000495429 — lncRNA, 1239 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000425094, ENST00000717699, ENST00000757781

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000425094 — 2 exons

Exon	Start	End
ENSE00001696777	111115547	111115678
ENSE00004033184	111113812	111114918

Expression profiles

Bgee: expression breadth ubiquitous, 139 present calls, max score 85.69.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0627 / max 4.1108, expressed in 38 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
138286	0.0627	38

Top tissues by expression

230 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.69	gold quality
ganglionic eminence	UBERON:0004023	69.13	gold quality
cortical plate	UBERON:0005343	68.95	gold quality
adenohypophysis	UBERON:0002196	64.90	gold quality
pituitary gland	UBERON:0000007	62.46	gold quality
ventricular zone	UBERON:0003053	62.15	gold quality
stromal cell of endometrium	CL:0002255	60.50	gold quality
tibial artery	UBERON:0007610	59.98	gold quality
popliteal artery	UBERON:0002250	59.97	gold quality
right hemisphere of cerebellum	UBERON:0014890	59.77	gold quality
left coronary artery	UBERON:0001626	59.76	gold quality
prefrontal cortex	UBERON:0000451	59.72	gold quality
right frontal lobe	UBERON:0002810	59.39	gold quality
Brodmann (1909) area 9	UBERON:0013540	58.78	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.75	gold quality
anterior cingulate cortex	UBERON:0009835	58.64	gold quality
hypothalamus	UBERON:0001898	58.62	gold quality
subcutaneous adipose tissue	UBERON:0002190	58.59	gold quality
cerebellar hemisphere	UBERON:0002245	58.44	gold quality
coronary artery	UBERON:0001621	58.36	gold quality
cerebellar cortex	UBERON:0002129	58.21	gold quality
omental fat pad	UBERON:0010414	58.00	gold quality
aorta	UBERON:0000947	57.96	gold quality
peritoneum	UBERON:0002358	57.95	gold quality
adipose tissue of abdominal region	UBERON:0007808	57.44	gold quality
cerebellum	UBERON:0002037	56.98	gold quality
right testis	UBERON:0004534	56.69	gold quality
ectocervix	UBERON:0012249	56.42	gold quality
neocortex	UBERON:0001950	56.28	gold quality
nucleus accumbens	UBERON:0001882	56.15	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.67

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.