ARHGEF7-IT1

Summary

ARHGEF7-IT1 (ARHGEF7 intronic transcript 1, HGNC:41408) is a long non-coding RNA gene on chromosome 13q34.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41408
Approved symbol	ARHGEF7-IT1
Name	ARHGEF7 intronic transcript 1
Location	13q34
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233644
Ensembl biotype	lncRNA
Entrez	100874371
RNAcentral	URS000043569B — lncRNA, 804 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000423329

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000423329 — 2 exons

Exon	Start	End
ENSE00001645772	111143546	111144264
ENSE00001717262	111122652	111122736

Expression profiles

Bgee: expression breadth broad, 100 present calls, max score 63.21.

Top tissues by expression

100 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cortical plate	UBERON:0005343	63.21	gold quality
ventricular zone	UBERON:0003053	62.58	gold quality
testis	UBERON:0000473	62.49	gold quality
left testis	UBERON:0004533	62.32	gold quality
ganglionic eminence	UBERON:0004023	61.65	gold quality
right testis	UBERON:0004534	61.41	gold quality
tonsil	UBERON:0002372	61.19	silver quality
skeletal muscle tissue	UBERON:0001134	56.61	gold quality
calcaneal tendon	UBERON:0003701	54.73	silver quality
gall bladder	UBERON:0002110	54.41	gold quality
islet of Langerhans	UBERON:0000006	53.59	gold quality
endometrium	UBERON:0001295	53.13	gold quality
placenta	UBERON:0001987	52.57	gold quality
popliteal artery	UBERON:0002250	52.50	gold quality
tibial artery	UBERON:0007610	52.50	gold quality
right lobe of liver	UBERON:0001114	52.35	gold quality
blood	UBERON:0000178	50.99	gold quality
prefrontal cortex	UBERON:0000451	50.48	gold quality
small intestine	UBERON:0002108	49.66	gold quality
bone marrow	UBERON:0002371	49.06	silver quality
muscle of leg	UBERON:0001383	48.99	gold quality
myometrium	UBERON:0001296	48.88	gold quality
gastrocnemius	UBERON:0001388	47.87	gold quality
multicellular organism	UBERON:0000468	47.79	gold quality
liver	UBERON:0002107	47.78	silver quality
subcutaneous adipose tissue	UBERON:0002190	47.47	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	47.47	gold quality
hindlimb stylopod muscle	UBERON:0004252	47.19	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	47.04	silver quality
ascending aorta	UBERON:0001496	46.25	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.64

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.