ARHGEF9-IT1

Summary

ARHGEF9-IT1 (ARHGEF9 intronic transcript 1, HGNC:41401) is a long non-coding RNA gene on chromosome Xq11.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41401
Approved symbol	ARHGEF9-IT1
Name	ARHGEF9 intronic transcript 1
Location	Xq11.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000231729
Ensembl biotype	lncRNA
Entrez	100874355
RNAcentral	URS0000A763C5 — lncRNA, 416 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000420917

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000420917 — 2 exons

Exon	Start	End
ENSE00001633244	63670196	63670341
ENSE00001765015	63671255	63671502

Expression profiles

Bgee: expression breadth ubiquitous, 103 present calls, max score 76.28.

Top tissues by expression

103 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	76.28	gold quality
colonic epithelium	UBERON:0000397	68.37	silver quality
bone marrow cell	CL:0002092	64.68	silver quality
skeletal muscle tissue	UBERON:0001134	63.48	silver quality
lymph node	UBERON:0000029	63.21	gold quality
bone marrow	UBERON:0002371	62.26	gold quality
tonsil	UBERON:0002372	61.32	silver quality
vermiform appendix	UBERON:0001154	60.69	gold quality
corpus callosum	UBERON:0002336	59.78	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	57.76	gold quality
prefrontal cortex	UBERON:0000451	56.92	gold quality
islet of Langerhans	UBERON:0000006	56.34	gold quality
blood	UBERON:0000178	55.99	gold quality
left coronary artery	UBERON:0001626	55.63	gold quality
monocyte	CL:0000576	55.56	gold quality
liver	UBERON:0002107	55.22	gold quality
ascending aorta	UBERON:0001496	55.17	gold quality
calcaneal tendon	UBERON:0003701	54.86	gold quality
thoracic aorta	UBERON:0001515	54.78	gold quality
right coronary artery	UBERON:0001625	54.14	gold quality
primary visual cortex	UBERON:0002436	54.09	gold quality
popliteal artery	UBERON:0002250	53.96	gold quality
urinary bladder	UBERON:0001255	53.92	gold quality
tibial artery	UBERON:0007610	53.87	gold quality
right lobe of liver	UBERON:0001114	53.62	gold quality
skin of abdomen	UBERON:0001416	53.47	gold quality
right ovary	UBERON:0002118	53.26	gold quality
myometrium	UBERON:0001296	52.75	gold quality
adrenal tissue	UBERON:0018303	52.49	gold quality
left adrenal gland cortex	UBERON:0035825	52.02	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.45

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.