ARLNC1

Summary

ARLNC1 (androgen receptor regulated long noncoding RNA 1, HGNC:53032) is a long non-coding RNA gene on chromosome 16q23.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53032
Approved symbol	ARLNC1
Name	androgen receptor regulated long noncoding RNA 1
Location	16q23.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	PRCAT47
Ensembl gene	ENSG00000260896
Ensembl biotype	lncRNA
OMIM	618053
Entrez	100996425
RNAcentral	URS00008E3A5B — lncRNA, 2343 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 54 — 54 lncRNA

ENST00000561519, ENST00000562231, ENST00000563626, ENST00000569356, ENST00000650661, ENST00000650680, ENST00000650729, ENST00000650926, ENST00000650943, ENST00000650965, ENST00000650974, ENST00000650994, ENST00000651072, ENST00000651082, ENST00000651118, ENST00000651119, ENST00000651120, ENST00000651153, ENST00000651276, ENST00000651313, ENST00000651389, ENST00000651473, ENST00000651478, ENST00000651521, ENST00000651582, ENST00000651594, ENST00000651617, ENST00000651631, ENST00000651640, ENST00000651724, ENST00000651730, ENST00000651739, ENST00000651780, ENST00000651859, ENST00000651980, ENST00000652020, ENST00000652077, ENST00000652137, ENST00000652149, ENST00000652187, ENST00000652198, ENST00000652211, ENST00000652275, ENST00000652349, ENST00000652403, ENST00000652422, ENST00000652507, ENST00000652512, ENST00000652538, ENST00000652646, ENST00000652662, ENST00000652668, ENST00000652701, ENST00000807040

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000561519 — 4 exons

Exon	Start	End
ENSE00002608356	80830494	80830757
ENSE00002615877	80870448	80870520
ENSE00002628894	80840119	80840222
ENSE00002629343	80837932	80838045

Expression profiles

Bgee: expression breadth ubiquitous, 132 present calls, max score 82.28.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.3026 / max 77.9235, expressed in 53 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
158257	0.2789	39
158256	0.0237	12

Top tissues by expression

132 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.28	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	78.49	gold quality
prostate gland	UBERON:0002367	67.43	gold quality
bone marrow cell	CL:0002092	67.14	silver quality
corpus callosum	UBERON:0002336	66.24	gold quality
sural nerve	UBERON:0015488	64.90	gold quality
hindlimb stylopod muscle	UBERON:0004252	64.11	gold quality
skeletal muscle tissue	UBERON:0001134	61.71	gold quality
ventricular zone	UBERON:0003053	61.61	gold quality
vermiform appendix	UBERON:0001154	60.96	gold quality
bone marrow	UBERON:0002371	60.86	gold quality
ganglionic eminence	UBERON:0004023	60.82	gold quality
tonsil	UBERON:0002372	60.18	gold quality
calcaneal tendon	UBERON:0003701	59.36	gold quality
muscle tissue	UBERON:0002385	59.16	gold quality
stromal cell of endometrium	CL:0002255	59.14	gold quality
cortical plate	UBERON:0005343	58.64	silver quality
placenta	UBERON:0001987	58.27	gold quality
prefrontal cortex	UBERON:0000451	58.16	gold quality
endometrium	UBERON:0001295	57.83	gold quality
leukocyte	CL:0000738	57.76	gold quality
monocyte	CL:0000576	57.61	gold quality
adrenal tissue	UBERON:0018303	55.77	gold quality
muscle of leg	UBERON:0001383	55.24	gold quality
lymph node	UBERON:0000029	55.19	gold quality
islet of Langerhans	UBERON:0000006	55.03	gold quality
urinary bladder	UBERON:0001255	54.35	gold quality
gastrocnemius	UBERON:0001388	54.29	gold quality
blood	UBERON:0000178	53.92	gold quality
primary visual cortex	UBERON:0002436	53.22	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	6.02

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LOC100996425 acts as a promoter in prostate cancer by mediating hepatocyte nuclear factor 4A and the AMPK/mTOR pathway. (PMID:34309216)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.