ARRDC1-AS1

Summary

ARRDC1-AS1 (ARRDC1 antisense RNA 1, HGNC:23395) is a long non-coding RNA gene on chromosome 9q34.3.

This transcribed locus is thought to be non-coding. Alternative splicing results in multiple transcript variants.

Source: NCBI Gene 85026 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:23395
Approved symbol	ARRDC1-AS1
Name	ARRDC1 antisense RNA 1
Location	9q34.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000203993
Ensembl biotype	lncRNA
Entrez	85026
RNAcentral	URS0000759D8C — lncRNA, 1507 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000371417, ENST00000496793, ENST00000623970, ENST00000663398, ENST00000749133, ENST00000749134, ENST00000749135, ENST00000749136

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000371417 — 3 exons

Exon	Start	End
ENSE00001455189	137617934	137618191
ENSE00001455191	137618531	137618878
ENSE00003875848	137615326	137616199

Expression profiles

Bgee: expression breadth ubiquitous, 216 present calls, max score 88.99.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 10.8841 / max 60.5064, expressed in 1775 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
103390	7.2974	1726
103388	3.2562	1579
103389	0.3305	156

Top tissues by expression

246 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adenohypophysis	UBERON:0002196	88.99	gold quality
kidney epithelium	UBERON:0004819	88.80	gold quality
pituitary gland	UBERON:0000007	87.72	gold quality
right lobe of thyroid gland	UBERON:0001119	87.69	gold quality
left lobe of thyroid gland	UBERON:0001120	86.98	gold quality
gastrocnemius	UBERON:0001388	86.98	gold quality
apex of heart	UBERON:0002098	86.66	gold quality
left adrenal gland cortex	UBERON:0035825	86.15	gold quality
right adrenal gland	UBERON:0001233	86.00	gold quality
mucosa of transverse colon	UBERON:0004991	85.97	gold quality
thyroid gland	UBERON:0002046	85.95	gold quality
muscle of leg	UBERON:0001383	85.93	gold quality
right hemisphere of cerebellum	UBERON:0014890	85.93	gold quality
right uterine tube	UBERON:0001302	85.88	gold quality
right adrenal gland cortex	UBERON:0035827	85.77	gold quality
adrenal cortex	UBERON:0001235	85.74	gold quality
upper arm skin	UBERON:0004263	85.58	gold quality
metanephros cortex	UBERON:0010533	85.55	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	85.54	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	85.41	gold quality
left adrenal gland	UBERON:0001234	85.40	gold quality
right testis	UBERON:0004534	85.37	gold quality
left testis	UBERON:0004533	85.29	gold quality
hindlimb stylopod muscle	UBERON:0004252	85.00	gold quality
cerebellar hemisphere	UBERON:0002245	84.93	gold quality
cerebellar cortex	UBERON:0002129	84.75	gold quality
spinal cord	UBERON:0002240	84.65	gold quality
putamen	UBERON:0001874	84.55	gold quality
amygdala	UBERON:0001876	84.50	gold quality
tibial nerve	UBERON:0001323	84.43	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.61

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Long noncoding RNA ARRDC1-AS1 is activated by STAT1 and exerts oncogenic properties by sponging miR-432-5p/PRMT5 axis in glioma. (PMID:33220929)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.