ARRDC3-AS1

Summary

ARRDC3-AS1 (ARRDC3 antisense RNA 1, HGNC:44145) is a long non-coding RNA gene on chromosome 5q14.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:44145
Approved symbol	ARRDC3-AS1
Name	ARRDC3 antisense RNA 1
Location	5q14.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	uc.168
Ensembl gene	ENSG00000281357
Ensembl biotype	lncRNA
Entrez	100129716
RNAcentral	URS000075DB7C — lncRNA, 2502 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 22 — 22 lncRNA

ENST00000625713, ENST00000629389, ENST00000630823, ENST00000656345, ENST00000661720, ENST00000664205, ENST00000664873, ENST00000690875, ENST00000701059, ENST00000778568, ENST00000778569, ENST00000778570, ENST00000778571, ENST00000778572, ENST00000778573, ENST00000778574, ENST00000778575, ENST00000778576, ENST00000778577, ENST00000778578, ENST00000778579, ENST00000778580

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000625713 — 3 exons

Exon	Start	End
ENSE00003766279	91418855	91420715
ENSE00003766580	91380349	91380924
ENSE00003767893	91418709	91418771

Expression profiles

Bgee: expression breadth ubiquitous, 161 present calls, max score 88.08.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 5.9011 / max 100.2225, expressed in 1543 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
57540	3.2664	1375
57541	2.6346	676

Top tissues by expression

252 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	88.08	gold quality
bone marrow cell	CL:0002092	86.01	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.88	gold quality
kidney epithelium	UBERON:0004819	78.60	gold quality
adrenal tissue	UBERON:0018303	76.83	gold quality
monocyte	CL:0000576	75.28	gold quality
leukocyte	CL:0000738	74.71	gold quality
left testis	UBERON:0004533	73.75	gold quality
right testis	UBERON:0004534	73.62	gold quality
islet of Langerhans	UBERON:0000006	72.46	gold quality
calcaneal tendon	UBERON:0003701	72.26	gold quality
testis	UBERON:0000473	71.97	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	71.81	gold quality
sural nerve	UBERON:0015488	71.01	gold quality
colonic epithelium	UBERON:0000397	70.97	gold quality
bone marrow	UBERON:0002371	70.28	gold quality
smooth muscle tissue	UBERON:0001135	70.22	gold quality
tibialis anterior	UBERON:0001385	69.70	silver quality
epithelial cell of pancreas	CL:0000083	69.45	gold quality
popliteal artery	UBERON:0002250	67.85	gold quality
tibial artery	UBERON:0007610	67.85	gold quality
ileal mucosa	UBERON:0000331	67.70	gold quality
rectum	UBERON:0001052	67.19	gold quality
tonsil	UBERON:0002372	67.02	gold quality
vermiform appendix	UBERON:0001154	66.50	gold quality
aorta	UBERON:0000947	66.43	gold quality
right atrium auricular region	UBERON:0006631	66.42	gold quality
cardiac atrium	UBERON:0002081	66.16	gold quality
right coronary artery	UBERON:0001625	66.10	gold quality
cortical plate	UBERON:0005343	65.96	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.30

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.