ASAH1-AS1
gene geneOn this page
Summary
ASAH1-AS1 (ASAH1 antisense RNA 1, HGNC:55603) is a long non-coding RNA gene on chromosome 8p22.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:55603 |
| Approved symbol | ASAH1-AS1 |
| Name | ASAH1 antisense RNA 1 |
| Location | 8p22 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Ensembl gene | ENSG00000245281 |
| Ensembl biotype | lncRNA |
| Entrez | 101929066 |
| RNAcentral | URS00007E3630 — lncRNA, 2309 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 58 — 58 lncRNA
ENST00000499554, ENST00000505114, ENST00000517747, ENST00000517798, ENST00000521775, ENST00000649327, ENST00000659561, ENST00000665050, ENST00000671237, ENST00000702451, ENST00000839452, ENST00000839453, ENST00000839454, ENST00000839455, ENST00000839456, ENST00000839457, ENST00000839458, ENST00000839459, ENST00000839460, ENST00000839461, ENST00000839462, ENST00000839463, ENST00000839464, ENST00000839465, ENST00000839466, ENST00000839467, ENST00000839468, ENST00000839469, ENST00000839470, ENST00000839471, ENST00000839472, ENST00000839473, ENST00000839474, ENST00000839475, ENST00000839476, ENST00000839477, ENST00000839478, ENST00000839479, ENST00000839480, ENST00000839481, ENST00000839482, ENST00000839483, ENST00000839484, ENST00000839485, ENST00000839486, ENST00000839487, ENST00000839722, ENST00000839723, ENST00000839724, ENST00000839725, ENST00000839726, ENST00000839727, ENST00000839728, ENST00000839729, ENST00000839730, ENST00000839731, ENST00000839732, ENST00000839733
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000499554 — 5 exons
| Exon | Start | End |
|---|---|---|
| ENSE00001959733 | 18095826 | 18096394 |
| ENSE00001961488 | 18087025 | 18087137 |
| ENSE00001964379 | 18086883 | 18086936 |
| ENSE00001978349 | 18084868 | 18084939 |
| ENSE00001985803 | 18085242 | 18085485 |
Expression profiles
Bgee: expression breadth ubiquitous, 134 present calls, max score 82.24.
Top tissues by expression
134 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| male germ line stem cell (sensu Vertebrata) in testis | CL:0000089 ∩ UBERON:0000473 | 82.24 | gold quality |
| cortical plate | UBERON:0005343 | 73.89 | gold quality |
| bone marrow cell | CL:0002092 | 73.85 | gold quality |
| sural nerve | UBERON:0015488 | 72.47 | silver quality |
| hindlimb stylopod muscle | UBERON:0004252 | 72.20 | gold quality |
| right lobe of thyroid gland | UBERON:0001119 | 72.01 | gold quality |
| colonic epithelium | UBERON:0000397 | 71.88 | silver quality |
| skeletal muscle tissue | UBERON:0001134 | 71.64 | gold quality |
| muscle of leg | UBERON:0001383 | 71.31 | gold quality |
| left lobe of thyroid gland | UBERON:0001120 | 71.20 | gold quality |
| primordial germ cell in gonad | CL:0000670 ∩ UBERON:0000991 | 71.12 | gold quality |
| gastrocnemius | UBERON:0001388 | 71.01 | gold quality |
| thyroid gland | UBERON:0002046 | 70.99 | gold quality |
| putamen | UBERON:0001874 | 70.03 | gold quality |
| nucleus accumbens | UBERON:0001882 | 69.07 | gold quality |
| muscle tissue | UBERON:0002385 | 69.01 | gold quality |
| calcaneal tendon | UBERON:0003701 | 68.92 | gold quality |
| prefrontal cortex | UBERON:0000451 | 68.70 | gold quality |
| heart left ventricle | UBERON:0002084 | 68.68 | gold quality |
| primary visual cortex | UBERON:0002436 | 68.64 | gold quality |
| islet of Langerhans | UBERON:0000006 | 68.63 | gold quality |
| caudate nucleus | UBERON:0001873 | 68.45 | gold quality |
| superior frontal gyrus | UBERON:0002661 | 68.25 | gold quality |
| cerebellar cortex | UBERON:0002129 | 67.96 | gold quality |
| cerebellum | UBERON:0002037 | 67.92 | gold quality |
| frontal cortex | UBERON:0001870 | 67.80 | gold quality |
| cerebellar hemisphere | UBERON:0002245 | 67.79 | gold quality |
| right lobe of liver | UBERON:0001114 | 67.54 | gold quality |
| dorsolateral prefrontal cortex | UBERON:0009834 | 67.53 | gold quality |
| C1 segment of cervical spinal cord | UBERON:0006469 | 67.46 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 0.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | no | 2.41 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): hereditary spastic paraplegia 53, spinal muscular atrophy-progressive myoclonic epilepsy syndrome