ASH1L-AS1

Summary

ASH1L-AS1 (ASH1L antisense RNA 1, HGNC:44146) is a long non-coding RNA gene on chromosome 1q22.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:44146
Approved symbol	ASH1L-AS1
Name	ASH1L antisense RNA 1
Location	1q22
Locus type	RNA, long non-coding
Status	Approved
Aliases	APPLE
Ensembl gene	ENSG00000235919
Ensembl biotype	lncRNA
Entrez	645676
RNAcentral	URS0002A67FA4 — lncRNA, 8036 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000452809, ENST00000456633

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000452809 — 2 exons

Exon	Start	End
ENSE00001667743	155562073	155562286
ENSE00001745209	155563250	155563944

Expression profiles

Bgee: expression breadth ubiquitous, 215 present calls, max score 86.38.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 8.6357 / max 610.9879, expressed in 1636 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
5628	7.0996	1508
5626	1.0839	581
5627	0.4522	225

Top tissues by expression

235 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	86.38	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.66	gold quality
oviduct epithelium	UBERON:0004804	80.49	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	79.88	gold quality
bronchial epithelial cell	CL:0002328	78.95	gold quality
sperm	CL:0000019	78.09	silver quality
gastrocnemius	UBERON:0001388	77.79	gold quality
bronchus	UBERON:0002185	77.64	gold quality
mucosa of paranasal sinus	UBERON:0005030	77.61	silver quality
tibia	UBERON:0000979	77.37	gold quality
muscle of leg	UBERON:0001383	77.30	gold quality
gingival epithelium	UBERON:0001949	76.73	silver quality
palpebral conjunctiva	UBERON:0001812	76.48	gold quality
monocyte	CL:0000576	74.58	gold quality
leukocyte	CL:0000738	74.30	gold quality
adenohypophysis	UBERON:0002196	74.18	gold quality
cartilage tissue	UBERON:0002418	74.16	gold quality
buccal mucosa cell	CL:0002336	73.93	gold quality
skin of hip	UBERON:0001554	73.75	gold quality
bone marrow cell	CL:0002092	73.46	gold quality
quadriceps femoris	UBERON:0001377	73.39	silver quality
biceps brachii	UBERON:0001507	73.35	silver quality
vastus lateralis	UBERON:0001379	73.17	silver quality
left lobe of thyroid gland	UBERON:0001120	73.01	gold quality
pituitary gland	UBERON:0000007	72.96	gold quality
thyroid gland	UBERON:0002046	72.59	gold quality
metanephros cortex	UBERON:0010533	72.57	gold quality
hindlimb stylopod muscle	UBERON:0004252	72.52	gold quality
popliteal artery	UBERON:0002250	72.48	gold quality
tibial artery	UBERON:0007610	72.48	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.69

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.