ASH1L-IT1

Summary

ASH1L-IT1 (ASH1L intronic transcript 1, HGNC:41449) is a long non-coding RNA gene on chromosome 1q22.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41449
Approved symbol	ASH1L-IT1
Name	ASH1L intronic transcript 1
Location	1q22
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000227773
Ensembl biotype	lncRNA
Entrez	106478976
RNAcentral	URS000017303B — lncRNA, 448 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000458371

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000458371 — 2 exons

Exon	Start	End
ENSE00001626007	155396010	155396402
ENSE00001751109	155396924	155396978

Expression profiles

Bgee: expression breadth ubiquitous, 114 present calls, max score 83.52.

Top tissues by expression

114 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.52	silver quality
colonic epithelium	UBERON:0000397	75.16	gold quality
sural nerve	UBERON:0015488	69.45	gold quality
bone marrow cell	CL:0002092	68.87	silver quality
ventricular zone	UBERON:0003053	68.72	gold quality
skeletal muscle tissue	UBERON:0001134	67.31	gold quality
bone marrow	UBERON:0002371	65.70	gold quality
calcaneal tendon	UBERON:0003701	65.68	gold quality
tonsil	UBERON:0002372	63.65	silver quality
adrenal tissue	UBERON:0018303	61.82	gold quality
corpus callosum	UBERON:0002336	60.82	gold quality
lymph node	UBERON:0000029	60.81	gold quality
liver	UBERON:0002107	59.20	gold quality
gall bladder	UBERON:0002110	58.32	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	57.53	gold quality
kidney	UBERON:0002113	56.98	gold quality
endometrium	UBERON:0001295	56.24	gold quality
islet of Langerhans	UBERON:0000006	55.20	gold quality
blood	UBERON:0000178	55.10	gold quality
superior frontal gyrus	UBERON:0002661	54.84	gold quality
vermiform appendix	UBERON:0001154	54.49	gold quality
muscle of leg	UBERON:0001383	54.41	gold quality
monocyte	CL:0000576	54.34	gold quality
cortex of kidney	UBERON:0001225	52.55	gold quality
metanephros cortex	UBERON:0010533	52.39	gold quality
prefrontal cortex	UBERON:0000451	52.37	gold quality
gastrocnemius	UBERON:0001388	52.29	gold quality
primary visual cortex	UBERON:0002436	52.10	gold quality
urinary bladder	UBERON:0001255	52.09	gold quality
placenta	UBERON:0001987	50.95	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.08

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.