ASIC4-AS1
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Summary
ASIC4-AS1 (ASIC4 antisense RNA 1, HGNC:40960) is a long non-coding RNA gene on chromosome 2q35.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:40960 |
| Approved symbol | ASIC4-AS1 |
| Name | ASIC4 antisense RNA 1 |
| Location | 2q35 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Ensembl gene | ENSG00000227432 |
| Ensembl biotype | lncRNA |
| Entrez | 105373885 |
| RNAcentral | URS00005249AE — lncRNA, 519 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 1 — 1 lncRNA
ENST00000429882
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000429882 — 2 exons
| Exon | Start | End |
|---|---|---|
| ENSE00001617074 | 219516696 | 219516877 |
| ENSE00001699287 | 219482073 | 219482409 |
Expression profiles
Bgee: expression breadth ubiquitous, 115 present calls, max score 95.78.
Top tissues by expression
115 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| male germ line stem cell (sensu Vertebrata) in testis | CL:0000089 ∩ UBERON:0000473 | 95.78 | gold quality |
| islet of Langerhans | UBERON:0000006 | 78.57 | gold quality |
| pituitary gland | UBERON:0000007 | 73.13 | gold quality |
| adenohypophysis | UBERON:0002196 | 69.25 | gold quality |
| popliteal artery | UBERON:0002250 | 67.67 | gold quality |
| tibial artery | UBERON:0007610 | 67.65 | gold quality |
| mucosa of stomach | UBERON:0001199 | 67.09 | gold quality |
| ectocervix | UBERON:0012249 | 66.40 | gold quality |
| ventricular zone | UBERON:0003053 | 66.27 | gold quality |
| hindlimb stylopod muscle | UBERON:0004252 | 66.13 | gold quality |
| right coronary artery | UBERON:0001625 | 66.09 | gold quality |
| descending thoracic aorta | UBERON:0002345 | 65.67 | gold quality |
| uterine cervix | UBERON:0000002 | 65.38 | gold quality |
| skeletal muscle tissue | UBERON:0001134 | 65.17 | gold quality |
| pancreas | UBERON:0001264 | 65.03 | gold quality |
| ascending aorta | UBERON:0001496 | 63.93 | gold quality |
| esophagogastric junction muscularis propria | UBERON:0035841 | 63.90 | gold quality |
| muscle layer of sigmoid colon | UBERON:0035805 | 63.87 | gold quality |
| thoracic aorta | UBERON:0001515 | 63.77 | gold quality |
| endocervix | UBERON:0000458 | 63.66 | gold quality |
| lower esophagus muscularis layer | UBERON:0035833 | 63.57 | gold quality |
| lower esophagus | UBERON:0013473 | 63.54 | gold quality |
| myometrium | UBERON:0001296 | 63.44 | gold quality |
| right hemisphere of cerebellum | UBERON:0014890 | 63.16 | gold quality |
| left coronary artery | UBERON:0001626 | 63.05 | gold quality |
| cerebellar hemisphere | UBERON:0002245 | 62.88 | gold quality |
| cerebellar cortex | UBERON:0002129 | 62.77 | gold quality |
| cerebellum | UBERON:0002037 | 62.61 | gold quality |
| primordial germ cell in gonad | CL:0000670 ∩ UBERON:0000991 | 61.47 | gold quality |
| urinary bladder | UBERON:0001255 | 61.38 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 0.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | no | 0.49 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): alacrima, achalasia, and intellectual disability syndrome, chromosomal instability with tissue-specific radiosensitivity, myopathy, centronuclear, 2, myopathy, centronuclear, 5